Contraception

This case explored a novel surgical method to fix levonorgestrel 52-mg intrauterine devices in patients with adenomyosis and uterine septum. The procedure is convenient and feasible, and successfully applied the technique in a 43-year-old p…

ObjectivesTo describe contraceptive use for pregnancy prevention among transgender men and gender diverse (TGD) individuals assigned female or intersex at birth (AFIAB) and explore whether contraceptive use differs by testosterone use.Study…

ObjectivesTo explore whether discussing contraceptive use with a healthcare provider is associated with current contraceptive use among transgender men and gender-diverse (TMGD) individuals.Study designIn 2019, we conducted a cross-sectiona…

OBJECTIVES: Evidence regarding risk for hysterectomy following treatment for benign gynecological conditions with a levonorgestrel-releasing intrauterine device (LNG-IUD) is limited. We assess whether race and ethnicity are associated with …

OBJECTIVE: We aimed to assess the effects of contraception with NuvaRing on ultrasound signs and symptoms of women with adenomyosis. STUDY DESIGN: We conducted a prospective self-controlled observational study on women with adenomyosis who…

ObjectivesExogenous estrogen is associated with growth of hepatocellular adenomas (HCAs), although the influence of progestin-only agents is unknown. We therefore evaluated the association of progestin-only agents on HCA progression compare…

ObjectivesTo estimate the hazard of incident idiopathic intracranial hypertension, a potentially blinding condition, among women using levonorgestrel intrauterine devices (LNG-IUD) compared to copper IUD, as conflicting associations have be…

ObjectiveWe aimed to qualitatively describe the contraceptive experiences of individuals with medical conditions and develop an explanatory model of contraceptive decision-making in this context.Study designWe conducted 41 interviews with p…

OBJECTIVES: We collected real-world data on the safety and clinical outcomes of the levonorgestrel-releasing intrauterine system (LNG-IUS) for heavy menstrual bleeding and dysmenorrhea. STUDY DESIGN: This was a prospective, multicenter, si…

ObjectiveTo develop a minimum data set, known as a core outcome set, for future abortion randomized controlled trials.Study designWe extracted outcomes from quantitative and qualitative systematic reviews of abortion studies to assess using…

ObjectivesTo determine if women with tubal patency experience more fluid loss compared to those with bilateral tubal occlusion following intrauterine instillation of fluid via a balloon catheter.Study designIn this prospective cohort pilot …

BackgroundPelvic pain has been associated with Essure, a permanent contraceptive implant. Here we describe histopathologic findings in long-term Essure users with chronic pelvic pain.MethodsWe descriptively evaluated and compared histopatho…

ObjectivesTo characterize reasons for hormonal contraceptive (HC) use in 1,455 African-American women, aged 23-35 years.Study designThe community-based cohort members were recruited from the Detroit, Michigan area in 2010-2012. HC history w…

OBJECTIVE: To explore perspectives on family planning among young people who perceive they are infertile or will have difficulty carrying a pregnancy to term owing to medical conditions or procedures. METHODS: This exploratory analysis exa…

ObjectiveTo compare the effects of chlormadinone acetate (CMA), dienogest (DNG) and drospirenone (DRSP) on prostaglandin biosynthesis in a human endometrial explants model.Study designHuman endometrial explants obtained by aspiration curett…

ObjectiveFollowing the 2016US presidential election, social media posts and news stories amplified concerns about the potential for reduced access to contraception under the incoming administration and urged women to seek long-acting revers…

CONTEXT: Depot medroxyprogesterone acetate (DMPA), a progestogen-only contraceptive injectable, has traditionally been formulated as a crystalline suspension delivered intramuscularly (IM) at a dose of 150mg/1.0mL. A new, lower dose formula…

BackgroundEndometriosis is a gynecological disorder that is associated with alterations in the immune system that contributes to its pathology as well as its associated infertility.Main findingsThis brief report summarizes our findings rela…

IntroductionThis study compares the efficacy of a levonorgestrel-releasing intrauterine system (LNG-IUS) and a low-dose combined oral contraceptive (COC) in reducing adenomyosis-related pain and bleeding.Materials and methodsA randomized cl…

Biology and reproductionDue to their size and anatomical similarity to humans, baboons make an excellent model for reproductive studies. Baboons have a simple short cervix, muscular uterus, ovaries just lateral to the uterus and similar vas…

ObjectiveTo demonstrate the feasibility of polidocanol foam (PF) as a nonsurgical method of female permanent contraception using a nonhuman primate model.Study designFour groups of adult female rhesus macaques underwent either transcervical…

BackgroundIt has been recognized for well over half a century that hormonal preparations designed as contraceptives are also capable of offering health benefits through the treatment and prevention of benign gynecological disease and even s…

BackgroundThe study was conducted to compare the levonorgestrel intrauterine system (LNG-IUS) and Copper T380A intrauterine device (IUD) in women with and without adenomyosis and to investigate the effects on menstruation and dysmenorrhea.S…