Histologic study of ovarian endometriosis after hormonal therapy
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This study examines histological changes in ovarian endometriosis following hormonal therapy, providing insights into treatment-induced tissue alterations.
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Abstract
To evaluate the persistence of endometriosis and the morphologic changes occurring in endometriotic foci after hormonal therapy, microsurgical resection of ovarian endometriosis was performed in 148 women. After hormonal therapy (n = 116), a high prevalence of active endometriosis without signs of degeneration was found. Mitotic index was similar in the group of untreated women (n = 32) and in the three groups of women treated either with lynestrenol (Organon, Oss, The Netherlands), gestrinone (Roussel UCLAF, Paris, France), or buserelin (Hoechst, Frankfurt, West Germany). In conclusion, hormonal treatment leads to an incomplete suppression of endometriotic foci.
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- Additional file 1 of Factors associated with recurrent endometriomas after surgical excision 2023
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- The presence of living endometrial cells in ovarian endometriotic cyst fluid may contribute to the recurrence of endometriosis after surgical excision of endometriomas 2022
- A narrative review of using GnRH analogues to reduce endometriosis recurrence after surgery: a double-edged sword 2021
- Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review 2021
- Perioperative Intervention by β-Blockade and NF-κB Suppression Reduces the Recurrence Risk of Endometriosis in Mice Due to Incomplete Excision 2019
- The perioperative period: a critical yet neglected time window for reducing the recurrence risk of endometriosis? 2019
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- An evidence-based evaluation of endometriosis-associated infertility 2003
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- last seen: 2026-10-16T06:09:50.462052+00:00
- openalex
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