Gestrinone combined with ultrasound‐guided aspiration and ethanol injection for treatment of chocolate cyst of ovary

Xiaoyun Wu, Xu Yun
In: Journal of Obstetrics and Gynaecology Research · 2014 · vol. 41(5) , pp. 712–716 · doi:10.1111/jog.12612 · PMID:25420776 · W1603314141
article OA: closed CC0 ⤵ 5 in-corpus citations
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Gestrinone combined with ultrasound-guided aspiration and ethanol injection significantly reduced ovarian chocolate cyst recurrence and increased effectiveness compared to aspiration and injection alone.

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Abstract

AIM: The aim of this study was to determine clinical performance of gestrinone combined with ultrasound-guided aspiration and ethanol injection in treating chocolate cyst of ovary. METHODS: Sixty-eight patients enrolled in this study were randomly divided into two groups: control group and combination treatment group. In the control group, 34 patients were treated with ultrasound-guided aspiration and ethanol injection. In the combination treatment group, 34 patients received gestrinone p.o. following ultrasound-guided aspiration and ethanol injection. RESULTS: The recurrence rate of chocolate cyst was 10-fold lower in the combination treatment group (2.94%, 1/34) than in the control group (29.4%, 10/34) at 12 months. The effective rate for reduction of chocolate cyst was significantly higher in the combination treatment group (94.12%, 32/34) than in the control group (64.71%, 22/34) (P = 0.009). CONCLUSION: Gestrinone combined with ultrasound-guided aspiration and ethanol injection therapy is an effective treatment for ovarian chocolate cyst with low recurrence rate.

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