Gestrinone combined with ultrasound-guided aspiration and ethanol injection for treatment of chocolate cyst of ovary

Xiaoyun Wu, Xu Yun, Yun Xu
Journal of Obstetrics and Gynaecology Research · 2014 · vol. 41(5) , pp. 712–716 · doi:10.1111/jog.12612 · PMID:25420776 · W1603314141
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Gestrinone combined with ultrasound-guided aspiration and ethanol injection significantly reduced ovarian chocolate cyst recurrence and increased effectiveness compared to aspiration and injection alone.

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Abstract

AIM: The aim of this study was to determine clinical performance of gestrinone combined with ultrasound-guided aspiration and ethanol injection in treating chocolate cyst of ovary. METHODS: Sixty-eight patients enrolled in this study were randomly divided into two groups: control group and combination treatment group. In the control group, 34 patients were treated with ultrasound-guided aspiration and ethanol injection. In the combination treatment group, 34 patients received gestrinone p.o. following ultrasound-guided aspiration and ethanol injection. RESULTS: The recurrence rate of chocolate cyst was 10-fold lower in the combination treatment group (2.94%, 1/34) than in the control group (29.4%, 10/34) at 12 months. The effective rate for reduction of chocolate cyst was significantly higher in the combination treatment group (94.12%, 32/34) than in the control group (64.71%, 22/34) (P = 0.009). CONCLUSION: Gestrinone combined with ultrasound-guided aspiration and ethanol injection therapy is an effective treatment for ovarian chocolate cyst with low recurrence rate.

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MeSH descriptors

Ethanol Gestrinone Ovarian Cysts Paracentesis Progestins Adult Combined Modality Therapy Ethanol Female Gestrinone Humans Middle Aged Ovarian Cysts Ovarian Cysts Ovarian Cysts Progestins Recurrence Treatment Outcome Ultrasonography, Interventional Young Adult

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