The knockdown of progesterone receptor isoform B (PR-B) promotes proliferation in immortalized endometrial stromal cells
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This study investigated the role of progesterone receptor isoform B (PR-B) in immortalized endometrial stromal cells and found that its knockdown promotes cell proliferation.
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References (21)
- Cell proliferation is increased in the endometrium of women with endometriosis via openalex
- Inhibition of Proliferation of Endometrial Stromal Cells by Trichostatin A, RU486, CDB-2914, N-Acetylcysteine, and ICI 182780 via openalex
- Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis via openalex
- Nuclear Factor-κB (NF-κB): An Unsuspected Major Culprit in the Pathogenesis of Endometriosis That Is Still at Large? via openalex
- Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis via openalex
- Prolonged stimulation with tumor necrosis factor-α induced partial methylation at PR-B promoter in immortalized epithelial-like endometriotic cells via openalex
- Promoter Hypermethylation of Progesterone Receptor Isoform B (PR-B) in Endometriosis via openalex
- Reduction of apoptosis and proliferation in endometriosis via openalex
- Spontaneous Apoptosis of Endometrial Tissue is Impaired in Women with Endometriosis via openalex
- W2109801386 via openalex
- W4211081176 via openalex
- W1569704074 via openalex
- W6658221620 via openalex
- W1972848037 via openalex
- W2003778314 via openalex
- W2011025558 via openalex
- W2038507723 via openalex
- W2065643273 via openalex
- W2092268704 via openalex
- W2108004598 via openalex
- W2109525253 via openalex
Cited by (26)
- From Retrograde Menstruation to Endometrial Determinism and a Brave New World of "Root Treatment" of Endometriosis: Destiny or a Fanciful Utopia? 2023
- Epigenetic Dysregulation in Endometriosis: Implications for Pathophysiology and Therapeutics 2023
- Aberrant epigenetic regulation of estrogen and progesterone signaling at the level of endometrial/endometriotic tissue in the pathomechanism of endometriosis 2022
- The gut microbiota: a double-edged sword in endometriosis 2022
- Estrogen- and Progesterone (P4)-Mediated Epigenetic Modifications of Endometrial Stromal Cells (EnSCs) and/or Mesenchymal Stem/Stromal Cells (MSCs) in the Etiopathogenesis of Endometriosis 2021
- Dioxin and endometriosis: a new possible relation based on epigenetic theory 2019
- Progesterone resistance in endometriosis: origins, consequences and interventions 2017
- Altered retinoid signaling compromises decidualization in human endometriotic stromal cells 2017
- Retinoid Metabolism in Endometriosis 2017
- Selective inhibition of prostaglandin E2 receptors EP2 and EP4 modulates DNA methylation and histone modification machinery proteins in human endometriotic cells 2015
- Correlation between dioxin and endometriosis: an epigenetic route to unravel the pathogenesis of the disease 2015
- Small RNA molecules in endometriosis: pathogenesis and therapeutic aspects 2014
- Epigenetic background of the most common non-oncologic gynecological diseases 2014
- Epigenetics in Endometriosis 2014
- The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis 2014
- Epigenetic aberration of gene expression in endometriosis 2013
- The Epigenetics of Endometriosis 2012
- Etude phénotypique des cellules endométriosiques profondes 2012
- Progesterone Resistance and Targeting the Progesterone Receptors: A Therapeutic Approach to Endometriosis 2012
- Effects of progestins on local estradiol biosynthesis and action in the Z-12 endometriotic epithelial cell line 2012
- Endometriosis expresses a molecular pattern consistent with decreased retinoid uptake, metabolism and action 2011
- Aberrant DNA methylation status of endometriosis: Epigenetics as the pathogenesis, biomarker and therapeutic target 2011
- Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis 2011
- Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo 2010
- Altered Retinoid Uptake and Action Contributes to Cell Survival in Endometriosis 2010
- Disrupted Cell Cycle Control in Cultured Endometrial Cells from Patients with Endometriosis Harboring the Progesterone Receptor Polymorphism PROGINS 2009
Source provenance
- europepmc
- last seen: 2026-06-11T06:19:48.454388+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:14:42.556217+00:00
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