Modern medical management of endometriosis

Kettel LM, L. Michael Kettel, L M Kettel, Hummel WP, William P. Hummel, W P Hummel
Obstetrics and Gynecology Clinics of North America · 1997 · vol. 24(2) , pp. 361–373 · doi:10.1016/s0889-8545(05)70309-0 · PMID:9163772 · W2156079493
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This paper reviews the current medical management strategies for endometriosis, focusing on hormonal therapies, pain management, and emerging treatment options.

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Abstract

The modern medical management of endometriosis has changed considerably since the first attempts were made to control this disease hormonally over four decades ago. Currently, there are multiple choices for the clinician and patient, including oral contraceptives, danazol, GnRH agonist analogues, and gestrinone. Several advances have been made in the use of GnRH agonists in preventing some of the untoward effects of prolonged hypoestrogenism. These add-back regimens provide the best therapy available today for prolonged medical control of endometriotic symptoms. The antiprogesterones (RU-486) hold promise for the future, but are still in the investigational stage of development.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Danazol Danazol Danazol Endometriosis Endometriosis Estrogen Antagonists Estrogen Antagonists Estrogen Antagonists Estrogen Replacement Therapy Estrogen Replacement Therapy Female Female Gestrinone Gestrinone Gestrinone Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Hormone Antagonists

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (65)

Cited by (24)

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License: CC0 · commercial use OK