MODERN MEDICAL MANAGEMENT OF ENDOMETRIOSIS

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AI-generated summary by claude@2026-06, 2026-06-07

This paper reviews the current medical management strategies for endometriosis, focusing on hormonal therapies, pain management, and emerging treatment options.

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Abstract

The modern medical management of endometriosis has changed considerably since the first attempts were made to control this disease hormonally over four decades ago. Currently, there are multiple choices for the clinician and patient, including oral contraceptives, danazol, GnRH agonist analogues, and gestrinone. Several advances have been made in the use of GnRH agonists in preventing some of the untoward effects of prolonged hypoestrogenism. These add-back regimens provide the best therapy available today for prolonged medical control of endometriotic symptoms. The antiprogesterones (RU-486) hold promise for the future, but are still in the investigational stage of development.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Danazol Danazol Endometriosis Estrogen Antagonists Estrogen Antagonists Estrogen Replacement Therapy Female Gestrinone Gestrinone Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Hormone Antagonists Hormone Antagonists Humans Mifepristone Mifepristone Progesterone Congeners Progesterone Congeners

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (65)

Cited by (25)

Source provenance

europepmc
last seen: 2026-08-02T06:10:09.037253+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:10:52.568893+00:00
License: CC0 · commercial use OK