The Role of Plant-Based Diets and Personalized Nutrition in Endometriosis Management: A Review

Marijana Matek Sarić, Tamara Sorić, Ana Sarić, Emili Marušić, Miran Čoklo, Mladen Mavar, Marija Ljubičić, Nataša Lisica Šikić
Medicina (Kaunas, Lithuania) · 2025 · vol. 61(7) , pp. 1264 · doi:10.3390/medicina61071264 · PMID:40731893 · PMC12299565 · W4412387030
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This review explores plant-based diets and personalized nutrition, including medicinal plants and addressing food sensitivities, as adjunctive approaches to manage endometriosis by reducing inflammation and modulating estrogen activity.

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Abstract

Endometriosis is a chronic, estrogen-dependent inflammatory condition that affects multiple organ systems and significantly impairs the quality of life in women of reproductive age. While conventional hormonal therapies may alleviate symptoms of endometriosis, they are also frequently associated with intolerable side effects. As a result, there is growing interest in complementary, non-invasive strategies to support long-term disease management. This review explores the potential of plant-based diets and personalized nutrition as adjunctive approaches in endometriosis care. Plant-based dietary patterns, which are rich in antioxidants, phytochemicals, dietary fiber, and essential micronutrients, have been shown to reduce systemic inflammation, modulate estrogen activity, and alleviate pelvic pain. Additionally, the use of medicinal plants, such as curcumin and ginger, has demonstrated anti-inflammatory and anti-proliferative effects in preclinical studies. Moreover, identifying and addressing individual food sensitivities, particularly to gluten, dairy, or fermentable oligosaccharides, disaccharides, monosaccharides, and polyols, may improve gastrointestinal and inflammatory symptoms in susceptible individuals. Future research should focus on high-quality clinical trials and integrative care models to evaluate the long-term efficacy, safety, and sustainability of these individualized nutritional interventions in the holistic management of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian Diet, Vegetarian

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

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