Importance of Medicinal Compounds from Traditional Plants for the Treatment of Endometriosis

In: Interdisciplinary Biotechnological Advances · 2023 · pp. 253–269 · doi:10.1007/978-981-99-4939-7_11 · W4388877021
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This chapter reviews medicinal plants and their active components for developing multitargeted therapeutic compounds to treat endometriosis, a gynecological disorder causing pelvic pain and infertility.

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This chapter discusses endometriosis and reviews medicinal plants and their active compounds as potential sources of multitargeted therapeutic candidates, describing the activity profiles of plant-derived compounds tested for gynecological uses and emphasizing their role in traditional medicine where resources are limited. It highlights the development of medicinal plant–derived compounds for endometriosis, positioning them within a broader landscape that includes advances in computational and chemical approaches to drug discovery. A major caveat is that the text is presented as a chapter-style overview rather than a new patient study or a systematic experimental assessment with reported efficacy estimates. This paper is centrally about endometriosis — it focuses on the activity profile of traditional plant medicinal compounds and their development as multitargeted endometriosis therapies.

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Abstract

Endometriosis is a challenging gynecological disorder that causes pelvic pain and infertility attributed to the prevalence of ectopic endometrial tissue outside the uterine tract. Based on the patient’s histology findings, it is typically identified by pathological lesions, endometritis, pyometra, and glandular cystic hyperplasia. Traditional medicines are thought to be the most reliable sources for the discovery of novel pharmaceuticals, notwithstanding recent developments in computational and chemical techniques. Endometriosis and other gynecological illnesses have been tested against a variety of therapeutic herbs and chemicals derived from plants. In healthcare areas with few resources, traditional medicine is still seen as the main treatment option, regardless of recent scientific progress and globalization. Plant-derived compounds were once thought to be a key source of modern medications and play a crucial biological role against some pathogenic organisms. Ever since the dawn of humanity, an increasing number of plants have been utilized as remedies. In communities all across the world, traditional medicine has been an essential resource for health for centuries, and it is still a cornerstone for some people who have unequal access to mainstream treatment, according to research conducted by the World Health Organization (WHO). This book chapter presents the activity profile of medicinal plants and their active components while highlighting the development of multitargeted endometriosis medicinal compounds. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

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Springer, Singapore. https://doi.org/10.1007/978-981-99-4939-7_11 Download citation DOI: https://doi.org/10.1007/978-981-99-4939-7_11 Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-99-4938-0 Online ISBN: 978-981-99-4939-7 eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)

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