An Overview of Treatments for Endometriosis
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Levonorgestrel-releasing IUDs, GnRH analogues, and laparoscopic ablation/excision alleviate endometriosis pain and increase pregnancy rates, but GnRH analogues, danazol, and depot progestagens carry higher risks of adverse events.
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Abstract
CLINICAL QUESTION: What treatments are associated with improved outcomes for women with endometriosis? BOTTOM LINE: The levonorgestrel-releasing intrauterine system (LNG-IUD), gonadotropin-releasing hormone analogues (GnRHa; nafarelin, leuprolide, buserelin, goserelin, triptorelin), laparoscopic ablation, and excision are associated with relief of pain due to endometriosis. Gonadotropin-releasing hormone analogues and laparoscopic ablation or excision are associated with increased clinical pregnancy rates in women with endometriosis. Gonadotropin-releasing hormone analogues, danazol, and depot progestagens are associated with a higher incidence of adverse events.
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References (5)
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- <i>Endometriosis and Infertility</i> via openalex
- W2132577372 via openalex
- W2163315477 via openalex
- W2165010366 via openalex
Cited by (50)
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- Azurocidin is associated with dienogest-resistance in ovarian endometriotic cysts 2024
- Combined with bioinformatics and machine learning, the diagnostic model, Immunological features and subtypes of stage IV endometriosis with infertility were analyzed 2024
- Holistic Approaches in Endometriosis - as an Effective Method of Supporting Traditional Treatment: A Systematic Search and Narrative Review 2024
- Reply: Strengthening patient education on endometriosis therapies 2024
- Flavonoids Quercetin and Kaempferol Are NR4A1 Antagonists and Suppress Endometriosis in Female Mice 2023
- Attitudes and perceptions of affected women towards endocrine endometriosis therapy: an international survey based on free-word association networks 2023
- Factors that Increase the Likelihood of Ovarian Endometriosis Relapsing after Surgical Excision: A Systematic Review and Meta-Analysis 2023
- Importance of Medicinal Compounds from Traditional Plants for the Treatment of Endometriosis 2023
- Safety and efficacy of microwave ablation for abdominal wall endometriosis: A retrospective study 2023
- Chinese Herbal Medicine, Alternative or Complementary, for Endometriosis-Associated Pain: A Meta-Analysis 2023
- Leptin Stimulates Endometriosis Development in Mouse Models 2022
- AVALIAÇÃO DE BIOMARCADORES EM MULHERES COM ENDOMETRIOSE E DOR USUÁRIAS DO IMPLANTE COM ETONOGESTREL OU SISTEMA INTRAUTERINO COM LEVONORGESTREL: ENSAIO CLÍNICO RANDOMIZADO 2022
- Changes in MCP‐1, HGF, and IGF‐1 expression in endometrial stromal cells, PBMCs, and PFMCs of endometriotic women following 1,25(OH)2D3 treatment 2022
- The use of progestin subdermal implants in the management of endometriosis-related pain symptoms and quality of life: a systematic review 2022
- Avaliação de dois biomarcadores e de escores de dor pélvica crônica associada à endometriose em usuárias do implante com etonogestrel e do sistema intrauterino com levonorgestrel de 52 mg por 24 meses; e avaliação das vivências dos parceiros destas mulheres após o tratamento 2022
- A Systematic Review of the Efficacy and Availability of Targeted Treatments for Central Sensitization in Women With Endometriosis 2022
- Additional file 4 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Thoracic endometriosis presented as catamental hemoptysis: a case series of a rare disease 2021
- The roles and functions of macrophages in endometriosis 2021
- Subcutaneous etonogestrel implant combined with endometrial ablation for the treatment of adenomyosis: two case reports 2021
- Additional file 8 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 6 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 3 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 5 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 10 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 2 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 9 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 7 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 4 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 6 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 10 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 5 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 7 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 3 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 1 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 8 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 12 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 1 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 12 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 2 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 11 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Additional file 9 of Cell subtypes and immune dysfunction in peritoneal fluid of endometriosis revealed by single-cell RNA-sequencing 2021
- Hsa_circ_0063526 promotes the development of endometriosis by sponging miRNA-141-5p 2021
- ARID1A and PGR proteins interact in the endometrium and reveal a positive correlation in endometriosis 2021
- An assessment of the efficacy and safety of dydrogesterone in women with ovarian endometrioma: An open‐label multicenter clinical study 2021
- Endometriosis: a guide to investigations and treatment in the emergency department 2021
- Knockdown hsa_circ_0063526 inhibits endometriosis progression via regulating the miR-141-5p / EMT axis and downregulating estrogen receptors 2021
- miR-202-3p overexpression attenuates endometriosis-like lesions by modulating YAP-dependent transcription of S100A6 in murine models 2020
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