Subcutaneous etonogestrel implant combined with endometrial ablation for the treatment of adenomyosis: two case reports
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Abstract
Adenomyosis is a common disease that affects many premenopausal women. Two patients with adenomyosis, aged 51 and 42 years, presented with dysmenorrhea and increased menstrual volume. They refused laparoscopy or laparotomy surgery and were not eligible for the levonorgestrel-releasing intrauterine system (LNG-IUS). The first patient underwent endometrial ablation and subcutaneous etonogestrel (ENG)-releasing implant placement at the same time. Her symptoms of dysmenorrhea and heavy menstruation improved significantly. When serum follicle-stimulating hormone (FSH) and estradiol (E2) levels suggested menopause, the ENG-releasing implant was removed. However, her abdominal pain recurred and was relieved by medication. For the second patient, an ENG-releasing implant was placed first, and her dysmenorrhea and heavy menstrual volume were relieved. However, the bleeding pattern changed from regular bleeding to prolonged bleeding, which troubled the patient. Endometrial ablation was performed 4 months later to solve the problem. Both patients had improved symptoms and were satisfied with the treatment. For patients with adenomyosis who refuse surgery and are not candidates for the use of LNG-IUS, an ENG-releasing implant combined with endometrial ablation may be an effective alternative.
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Cites (3)
- An Overview of Treatments for Endometriosis 2015
- Treatment of rectovaginal endometriosis with the etonogestrel-releasing contraceptive implant 2019
- Treatment of Adenomyosis with Subcutaneous Etonogestrel Implants: A Clinical Observational Study in 17 Patients 2018
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References (16)
- An Overview of Treatments for Endometriosis via openalex
- Treatment of Adenomyosis with Subcutaneous Etonogestrel Implants: A Clinical Observational Study in 17 Patients via openalex
- Treatment of rectovaginal endometriosis with the etonogestrel-releasing contraceptive implant via openalex
- W2042374015 via openalex
- W2135726992 via openalex
- W2160681905 via openalex
- W2736047291 via openalex
- W2790094279 via openalex
- W2899183806 via openalex
- W2972387997 via openalex
- W3002387620 via openalex
- W3041095010 via openalex
- W1842567327 via openalex
- W6644905698 via openalex
- W1978438749 via openalex
- W1982151888 via openalex
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