Dioxin concentrations in women with endometriosis
article
OA: closed
CC0
⤵ 95 in-corpus citations
AI-generated summary
This study measured dioxin concentrations in infertile women, finding a significantly higher prevalence of dioxin positivity in those with endometriosis compared to controls.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
The concentrations of the enviromental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin were measured in the blood of 44 infertile women with endometriosis (study group), and in 35 age-matched women with tubal infertility (control group). Eight women with endometriosis (18%) were dioxin positive as compared to one woman (3%) in the controls (P = 0.04). Although the concentrations of dioxin did not seem to be directly correlated with the severity of endometriosis, these observations contribute to the accumulating data linking dioxin to endometriosis in humans.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (8)
- Dioxin pollution and endometriosis in Belgium via openalex
- Endometriosis in Rhesus Monkeys (Macaca mulatta) Following Chronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin via openalex
- W2026768246 via openalex
- W2068973221 via openalex
- W1994302562 via openalex
- W2177359510 via openalex
- W2477008945 via openalex
- W3015674599 via openalex
Cited by (50)
- Effectiveness of hysterectomy in endometriosis treatment 2024
- Unravelling the Complexity of Endometriosis: Insights into its Multifactorial Etiology and Clinical Management 2023
- Evidence of Dioxin as Endocrine Disrupting Chemicals in the Development of Endometriosis: A Narrative Review 2023
- Environmental Factors and Endometriosis 2021
- Environmental exposures to endocrine disrupting chemicals (EDCs) and their role in endometriosis: a systematic literature review 2020
- NAT2 gene polymorphisms and endometriosis risk: A PRISMA-compliant meta-analysis 2019
- Endometriosis-associated ovarian cancer: What have we learned so far? 2019
- Associations of perinatal characteristics with endometriosis: a nationwide birth cohort study 2019
- Associations between internal exposure levels of persistent organic pollutants in adipose tissue and deep infiltrating endometriosis with or without concurrent ovarian endometrioma 2017
- Endometriosis 2017
- Polychlorinated biphenyls and its potential role in endometriosis 2017
- Epidemiological and Clinical Risk Factors for Endometriosis 2017
- Female Reproductive Disorders, Diseases, and Costs of Exposure to Endocrine Disrupting Chemicals in the European Union 2016
- Association between glutathione S-transferase M1/T1 gene polymorphisms and susceptibility to endometriosis: A systematic review and meta-analysis 2016
- Correlation between dioxin and endometriosis: an epigenetic route to unravel the pathogenesis of the disease 2015
- Increased levels of dioxin-like substances in adipose tissue in patients with deep infiltrating endometriosis 2015
- Molecular aspects of development and regulation of endometriosis 2014
- Peptide inhibitors of angiogenesis in endometriosis and the female reproductive system 2014
- The influence of perinatal and current dioxin and PCB exposure on reproductive parameters (sex-ratio, menstrual cycle characteristics, endometriosis, semen quality, and prematurity): a review 2014
- Environmental Influences on the Development of Endometriosis 2013
- <i>In utero</i> exposure and endometriosis 2013
- Bisphenol A and phthalates and endometriosis: the Endometriosis: Natural History, Diagnosis and Outcomes Study 2013
- Persistent Lipophilic Environmental Chemicals and Endometriosis: The ENDO Study 2012
- Assessing Chemical Mixtures and Human Health: Use of Bayesian Belief Net Analysis 2012
- Endometriosis 2012
- Early Origins of Endometriosis: Role of Endocrine Disrupting Chemicals 2011
- Developmental dioxin exposure and endometriosis 2011
- O papel dos desreguladores endócrinos na fisiopatologia da endometriose: revisão da literatura 2010
- Association between <i>GSTM1</i> gene polymorphism in Iranian patients with endometriosis 2010
- Advances in the genetics of endometriosis 2010
- Dioxins in ascites and serum of women with endometriosis: a pilot study 2010
- Increased exposure to dioxin-like compounds is associated with endometriosis in a case–control study in women 2010
- Organochlorine pesticides and endometriosis 2010
- Possible aggravating impact of gene polymorphism in women with endometriosis. 2009
- Endometriosis and Organochlorinated Environmental Pollutants: A Case–Control Study on Italian Women of Reproductive Age 2009
- Environmental immune disruption: a comorbidity factor for reproduction? 2008
- <i>Endometriosis and Infertility</i> 2008
- Evaluation of the Phthalate Esters in South Indian Women with Endometriosis 2008
- Serum dioxins, polychlorinated biphenyls, and endometriosis: A case-control study in Atlanta 2008
- Endometriosis genital y extragenital 2008
- The association between heavy metals, endometriosis and uterine myomas among premenopausal women: National Health and Nutrition Examination Survey 1999-2002 2008
- Interaction between cytochrome P450 gene polymorphisms and serum organochlorine TEQ levels in the risk of endometriosis 2007
- Single nucleotide polymorphisms and haplotypes of the genes encoding the CYP1B1 in Korean women: No association with advanced endometriosis 2007
- Endométriose génitale et extragénitale 2007
- Environmental dioxin compounds as the cause of endometriosis and other diseases 2007
- Endometriosis Among Women Exposed to Polybrominated Biphenyls 2007
- The link between environmental toxicant exposure and endometriosis 2007
- Organochlorines and endometriosis: A mini-review 2007
- High plasma concentrations of polychlorinated biphenyls and phthalate esters in women with endometriosis: a prospective case control study 2006
- Impaired NK-cell-mediated cytotoxic activity and cytokine production in patients with endometriosis: A possible role for PCBs and DDE 2006
Source provenance
- europepmc
- last seen: 2026-08-23T09:30:01.253652+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:10:52.568893+00:00
- unpaywall
- last seen: 2026-08-23T06:29:45.520198+00:00
License: CC0
· commercial use OK