Diagnostic Accuracy of Transvaginal Ultrasound and Magnetic Resonance Imaging for Adenomyosis: Systematic Review and Meta-Analysis and Review of Sonographic Diagnostic Criteria

Linly Liu, Liu L, Wentao Li, Mathew Leonardi, Condous G, George Condous, G. Condous, Fabrício da Silva Costa, Fabricio Da Silva Costa, Mol BW, Ben W. Mol, Lufee Wong
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2021 · vol. 40(11) , pp. 2289–2306 · doi:10.1002/jum.15635 · PMID:33502767 · W3124689699
Systematic review / meta-analysis OA: closed CC0 ⤵ 37 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-06 ⓘ

This meta-analysis found transvaginal ultrasound and MRI have high, comparable diagnostic accuracy for adenomyosis, with echogenic subendometrial lines and buds being the best individual sonographic criterion.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

We aim to first systematically review and perform a meta-analysis of the diagnostic accuracy of transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI) and, second, to evaluate the accuracy of various sonographic diagnostic criteria for adenomyosis. A search of PubMed and Embase yielded 32 eligible studies. In diagnosing adenomyosis, the diagnostic performance of TVUS was found to be high and comparable to the performance of MRI. Of the eight sonographic criteria, only five were assessable. The best individual criterion was echogenic subendometrial lines and buds. Limited data exist for the various sonographic criteria, and further studies are required to compare their performance.

My notes (saved in your browser only)

Condition tags

endometriosisadenomyosis

MeSH descriptors

Adenomyosis Adenomyosis Adenomyosis Endometriosis Endometriosis Female Female Humans Humans Magnetic Resonance Imaging Magnetic Resonance Imaging Sensitivity and Specificity Sensitivity and Specificity Ultrasonography Ultrasonography

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (58)

Cited by (42)

Source provenance

europepmc
last seen: 2026-10-19T06:17:24.038039+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:29:46.384990+00:00
unpaywall
last seen: 2026-09-03T06:36:50.994332+00:00
License: CC0 · commercial use OK