Effect of dienogest on pain and ovarian endometrioma occurrence after laparoscopic resection of uterosacral ligaments with deep infiltrating endometriosis

Akiyoshi Yamanaka, Yamanaka A, Tomonori Hada, Matsumoto T, Tsuyoshi Matsumoto, Kanno K, Kiyoshi Kanno, Akira Shirane, A Shirane, Shirane A, Shiori Yanai, Yanai S, Nakajima S, S. Nakajima, Saori Nakajima, Ebisawa K, K. Ebisawa, Keiko Ebisawa, Yoshiaki Ota, Ota Y, M. Andou, Andou M, Masaaki Andou
European journal of obstetrics, gynecology, and reproductive biology · 2017 · vol. 216 , pp. 51–55 · doi:10.1016/j.ejogrb.2017.07.014 · PMID:28728071 · W2735845128
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This study investigated the impact of dienogest on pain and endometrioma recurrence following laparoscopic uterosacral ligament resection for deep infiltrating endometriosis.

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Abstract

OBJECTIVE: To evaluate the effect of dienogest (DNG) in preventing the occurrence of pain and endometriomas after laparoscopic resection of uterosacral ligaments (USLs) with deep infiltrating endometriosis (DIE). STUDY DESIGN: This retrospective analysis included 126 patients who underwent laparoscopic resection of USLs with DIE followed by postoperative administration of DNG or no medication. Every 6 months postoperatively, patients answered questions and underwent ultrasound examination to identify pain and/or endometrioma. RESULT: There were three (5.0%) cases of endometrioma in 59 patients from the DNG group and 21 (31.3%) cases in 67 patients from the no medication group (P=0.0002). Pain returned to preoperative levels in eight (11.9%) cases in the no medication group. No recurrence of pain occurred in the DNG group (P=0.0061). CONCLUSION: The administration of DNG after resection of USLs with DIE significantly reduces the occurrence rate of endometriosis-related pain and endometriomas.

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Condition tags

endometriosisdie_deep_infiltratingendometrioma

MeSH descriptors

Endometriosis Hormone Antagonists Nandrolone Ovarian Diseases Pain Peritoneal Diseases Endometriosis Endometriosis Endometriosis Female Female Hormone Antagonists Hormone Antagonists Humans Humans Laparoscopy Laparoscopy Nandrolone Nandrolone Nandrolone

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (25)

Cited by (24)

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