The prognostic significance of adenomyosis in endometrial carcinoma

J B Hall, James B. Hall, Hall JB, Young RH, R H Young, Robert H. Young, James H. Nelson, J H Nelson, Nelson JH Jr
Gynecologic Oncology · 1984 · vol. 17(1) , pp. 32–40 · doi:10.1016/0090-8258(84)90057-x · PMID:6693051 · W2095326899
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This study investigated the prognostic significance of adenomyosis in patients diagnosed with endometrial carcinoma.

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Abstract

Depth of myometrial invasion is accepted as one of the most important prognostic factors in carcinoma of the endometrium. In an effort to define the significance of adenomyosis containing adenocarcinoma as it relates to myometrial invasion, 52 cases of Stage I adenocarcinoma with coexisting adenomyosis were identified. A subset of 11 cases was noted to have adenocarcinoma in adenomyosis, invasive to a depth greater than would have been appreciated had this entity not been identified. These 11 cases had a 100% 5-year survival, suggesting that adenocarcinoma in adenomyosis does not indicate a more ominous prognosis. The depth of invasion into the myometrium proper is the significant prognostic factor. The pathologist must be able to differentiate these two distinct entities to accurately assess prognosis.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometriosis Uterine Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma Adult Aged Carcinoma, Squamous Cell Carcinoma, Squamous Cell Carcinoma, Squamous Cell Endometriosis Endometriosis Female Humans Middle Aged Neoplasm Invasiveness Neoplasm Staging Prognosis Uterine Neoplasms Uterine Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (31)

Cited by (26)

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