Adenomyosis and Endometrial Carcinoma
This paper reviews the debated link between adenomyosis and endometrial cancer, noting cases of cancer within ectopic endometrium and the diagnostic challenges.
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This chapter examines whether adenomyosis predisposes to endometrial cancer, given its proposed links to hyper-estrogenism and increased “invasiveness,” while also noting that early, non-invasive diagnosis is difficult. It summarizes that research is hindered by challenges in determining whether cancer arises in eutopic versus ectopic endometrium, including the rarity of reports describing cancer identified solely in ectopic endometrium within the myometrium. The chapter reports that cancer present within adenomyosis does not appear to adversely affect prognosis, while emphasizing caution due to the limited number of published studies. This paper is centrally about endometriosis and adenomyosis — specifically, it focuses on adenomyosis and its debated relationship to endometrial carcinoma, with endometriosis mentioned in the broader context of hormone-dependent uterine conditions.
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References (54)
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