Fertility preservation of polypoid endometriosis: Case series and literature review

S Miyoshi, Sayuri Miyoshi, Ken Yamaguchi, Yoshitsugu Chigusa, Masumi Sunada, Koji Yamanoi, Akihito Horie, Junzo Hamanishi, Eiji Kondoh, Masaki Mandai
Journal of Obstetrics and Gynaecology Research · 2021 · vol. 48(2) , pp. 502–509 · doi:10.1111/jog.15096 · PMID:34766411 · W3212693223
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This case series reports three successful fertility-preserving treatments for polypoid endometriosis, with two patients achieving live births, and reviews literature for preoperative diagnostic clues.

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Abstract

Polypoid endometriosis (PE) is a rare distinctive variant of endometriosis with morphological features resembling malignant tumors. Although a surgical procedure is usually performed for the treatment and diagnosis of PE, fertility preservation is usually desired in cases of reproductive age. However, there have been no reports of fertility-preserving treatments resulting in live births. In this study, we report three cases of PE that were diagnosed preoperatively or intraoperatively, leading to fertility preservation. Intraoperative pathological diagnosis, hysteroscopy, and hormone therapy before treatment were useful for preoperative diagnosis in the three cases. Two of the three patients got pregnant and the pregnancy progressed to a live birth. We also performed a literature review to identify the clinical characteristics indicative of the preoperative diagnosis of PE.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Fertility Preservation Female Fertility Humans Hysteroscopy Live Birth Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (42)

Cited by (4)

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License: CC0 · commercial use OK