MR findings of polypoid endometriosis of female genital organs: report of three cases

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MR imaging features including solid/microcystic or multilocular patterns and nodule morphology are helpful clues for diagnosing polypoid endometriosis, which can avoid overtreatment and allow for fertility preservation.

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This paper reports three cases of polypoid endometriosis involving female genital organs and describes characteristic MRI findings in relation to histopathology. Across the cases, nodules showed solid and microcystic or multilocular patterns corresponding to dilated endometrial glands, with helpful morphologic features (multilobulated or polypoid shape), and previously reported imaging traits such as T2 signal similar to endometrium, contrast-enhanced T1 similarity to endometrium, hypointense T2 rim, lack of diffusion restriction, and T1 hyperintense foci. Two patients were diagnosed preoperatively based on these MRI findings, and fertility-preserving treatment was given to one patient. The main limitation is that the evidence is based on only three case reports, which does not establish diagnostic performance beyond these examples. This paper is centrally about endometriosis — it focuses on MRI diagnosis of polypoid endometriosis of female genital organs.

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Abstract

Polypoid endometriosis is a benign, rare variant of endometriosis that forms polypoid nodules mimicking malignant tumors. For three cases of polypoid endometriosis of female genital organs, this report presents characteristic MR imaging features reflecting the histopathological findings. The solid and microcystic pattern or the multilocular pattern both reflecting dilated endometrial glands, and characteristic morphology of the nodules, multilobulated or polypoid-shaped, were helpful diagnostic clues present in these three cases. Earlier reported MR findings were also recognized, including signal intensity similar to that of the endometrium on T2-weighted image and contrast enhanced T1-weighted image, hypointense rim on T2-weighted image, lack of diffusion restriction, and hyperintense foci on T1-weighted image. Two cases were diagnosed preoperatively based on MR imaging findings as polypoid endometriosis. Fertility-preserving treatment was administered for one patient. Preoperative inference of polypoid endometriosis from MR imaging can avoid overtreatment and lead to fertility preservation.
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Abstract

Polypoid endometriosis is a benign, rare variant of endometriosis that forms polypoid nodules mimicking malignant tumors. For three cases of polypoid endometriosis of female genital organs, this report presents characteristic MR imaging features reflecting the histopathological findings. The solid and microcystic pattern or the multilocular pattern both reflecting dilated endometrial glands, and characteristic morphology of the nodules, multilobulated or polypoid-shaped, were helpful diagnostic clues present in these three cases. Earlier reported MR findings were also recognized, including signal intensity similar to that of the endometrium on T2-weighted image and contrast enhanced T1-weighted image, hypointense rim on T2-weighted image, lack of diffusion restriction, and hyperintense foci on T1-weighted image. Two cases were diagnosed preoperatively based on MR imaging findings as polypoid endometriosis. Fertility-preserving treatment was administered for one patient. Preoperative inference of polypoid endometriosis from MR imaging can avoid overtreatment and lead to fertility preservation. Similar content being viewed by others

References

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Ethical approval All procedures performed in studies involving human participants were conducted in accordance with ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. For a study of this type, formal consent is not required. Informed consent The requirement for written informed consent was waived for this case report based on the opt-out system of our institution. Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions About this article Cite this article Yajima, R., Kido, A., Minamiguchi, S. et al. MR findings of polypoid endometriosis of female genital organs: report of three cases. Abdom Radiol 47, 1968–1974 (2022). https://doi.org/10.1007/s00261-022-03530-4 Received: Revised: Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s00261-022-03530-4

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endometriosis

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Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

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