Vaginal Polypoid Endometriosis Simulating Neoplasia in a Young Woman

Vatsla Dadhwal, Dadhwal V, Dipika Deka, Deka D, Mathur S, Sandeep Mathur, Seema Kaushal, Kaushal S, Aparna Sharma, Aparna K Sharma, Sharma AK, Suneeta Mittal, Mittal S
Journal of lower genital tract disease · 2012 · vol. 16(3) , pp. 318–321 · doi:10.1097/lgt.0b013e318241052b · PMID:22460274 · W2010925919
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-13 ⓘ

This case report describes a young woman with vaginal polypoid endometriosis that did not respond to medical treatment but regressed after bilateral oophorectomy.

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This case report describes a 27-year-old nulliparous woman presenting with lower abdominal pain and vaginal bleeding, who was diagnosed with vaginal polypoid endometriosis mimicking neoplasia. Initial management included myomectomy and GnRH agonist therapy, but the vaginal masses failed to regress, necessitating bilateral salpingo-oophorectomy and ureteric reimplantation due to extensive pelvic involvement and hydronephrosis. The authors note that while medical treatment was ineffective, surgical removal of the ovaries led to significant regression of the widespread vaginal lesions. This paper is centrally about endometriosis — specifically a rare presentation of vaginal polypoid disease requiring aggressive surgical intervention after medical therapy failed.

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Abstract

OBJECTIVE: The study aimed to describe a case of vaginal polypoid endometriosis and its management. MATERIALS AND METHODS: This study is a case report. The patient was a nulliparous woman aged 27 years who presented with pain in her lower abdomen and continuous bleeding per vaginum for 2 months. On speculum examination, multiple, smooth, polypoid masses were seen arising all around the vaginal fornices; cervix was healthy. Ultrasound revealed a bulky uterus with a 5 × 6-cm fibroid in the posterior wall with echogenic area adjacent to cervix and gross left hydroureteronephrosis. The right kidney was removed 6 years consequent to pyonephrosis. Biopsy of the vaginal polypoidal mass was reported as vaginal polypoid endometriosis. The patient was planned for myomectomy and vaginal mass excision. On examination under anesthesia, the base of polypoid mass was thick and fixed and could not be excised completely. Myomectomy was done. Postoperatively, the patient received 3 injections of gonadotropin-releasing hormone agonist, but the size of the mass did not decrease. She was then planned for ureteric reimplantation and panhysterectomy. Hysterectomy was not possible because of extensive parametrial involvement, but Boari flap ureteric implantation with bilateral salpingo-oophorectomy was done. RESULTS: Vaginal polypoid endometriosis did not respond to medical treatment. However, the widespread vaginal polypoidal masses regressed significantly after oophorectomy. CONCLUSION: Bilateral oophorectomy was resorted to as an option in this case of vaginal polypoid and extensive pelvic endometriosis not amenable to medical treatment and surgical excision.
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Objective

The study aimed to describe a case of vaginal polypoid endometriosis and its management.

Materials and methods

This study is a case report. The patient was a nulliparous woman aged 27 years who presented with pain in her lower abdomen and continuous bleeding per vaginum for 2 months. On speculum examination, multiple, smooth, polypoid masses were seen arising all around the vaginal fornices; cervix was healthy. Ultrasound revealed a bulky uterus with a 5 × 6-cm fibroid in the posterior wall with echogenic area adjacent to cervix and gross left hydroureteronephrosis. The right kidney was removed 6 years consequent to pyonephrosis. Biopsy of the vaginal polypoidal mass was reported as vaginal polypoid endometriosis. The patient was planned for myomectomy and vaginal mass excision. On examination under anesthesia, the base of polypoid mass was thick and fixed and could not be excised completely. Myomectomy was done. Postoperatively, the patient received 3 injections of gonadotropin-releasing hormone agonist, but the size of the mass did not decrease. She was then planned for ureteric reimplantation and panhysterectomy. Hysterectomy was not possible because of extensive parametrial involvement, but Boari flap ureteric implantation with bilateral salpingo-oophorectomy was done.

Results

Vaginal polypoid endometriosis did not respond to medical treatment. However, the widespread vaginal polypoidal masses regressed significantly after oophorectomy.

Conclusion

Bilateral oophorectomy was resorted to as an option in this case of vaginal polypoid and extensive pelvic endometriosis not amenable to medical treatment and surgical excision.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Polyps Vaginal Diseases Adult Biopsy, Needle Diagnosis, Differential Endometriosis Endometriosis Endometriosis Female Follow-Up Studies Humans Immunohistochemistry Ovariectomy Ovariectomy Polyps Polyps Polyps Rare Diseases Risk Assessment

Citation neighborhood

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