Effectiveness of presacral neurectomy in women with severe dysmenorrhea caused by endometriosis who were treated with laparoscopic conservative surgery: A 1-year prospective randomized double-blind controlled trial

Zullo F, Fulvio Zullo, Stefano Palomba, Errico Zupi, Tiziana Russo, Russo T, Michele Morelli, Morelli M, Fulvio Cappiello, P Mastrantonio, Pasquale Mastrantonio, Cappiello F, Mastrantonio P
American journal of obstetrics and gynecology · 2003 · vol. 189(1) , pp. 5–10 · doi:10.1067/mob.2003.358 · PMID:12861130 · W2147738706
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This study evaluated the effectiveness of presacral neurectomy in women with severe dysmenorrhea due to endometriosis who underwent laparoscopic conservative surgery.

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Abstract

ObjectiveThe purpose of this study was to assess the effectiveness of presacral neurectomy in women with severe dysmenorrhea caused by endometriosis that was treated with conservative surgical intervention.Study designOne hundred forty-one sexually active women of fertile age with chronic severe dysmenorrhea caused by endometriosis were treated with conservative laparoscopic surgery. Patients were assigned randomly to not receive (group A) or receive (group B) presacral neurectomy. At 6 and 12 months after the surgical procedures, the cure rate was evaluated in each patient. The frequency and severity of dysmenorrhea, dyspareunia, and chronic pelvic pain were also evaluated at the same time intervals.ResultsThe cure rate was significantly higher in group B compared with group A at a follow-up examination at 6 months (87.3% vs 60.3%) and 12 months (85.7% vs 57.1%). At follow-up visits, the frequency and severity of dysmenorrhea, dyspareunia, and chronic pelvic pain were significantly lower in both groups compared with baseline values; in particular, significantly lower values were observed in group B versus group A for the severity.ConclusionPresacral neurectomy improves the cure rate in women who are treated with conservative laparoscopic surgery for severe dysmenorrhea caused by endometriosis.

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Condition tags

dysmenorrheadyspareuniaendometriosischronic_pelvic_pain

MeSH descriptors

Denervation Dysmenorrhea Endometriosis Laparoscopy Laparoscopy Pelvis Adult Denervation Double-Blind Method Dysmenorrhea Dysmenorrhea Dyspareunia Dyspareunia Endometriosis Female Humans Pelvic Pain Pelvic Pain Pelvis Postoperative Complications

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