Association between MIND diet its components with endometriosis risk: secondary results from a case-control study

Morvarid Noormohammadi, Seyed Mojtaba Ghoreishy, Sakine Ghasemisedaghat, Minoo HasanRashedi, Minoo Hasan-Rashedi, Zahra Saeedirad, Ghazaleh Eslamian, Seyyedeh Neda Kazemi, Elahe Nematifard, Bahram Rashidkhani, Robabeh Taheripanahe, Mehran Nouri
Scientific reports · 2025 · vol. 15(1) , pp. 19201 · doi:10.1038/s41598-025-04593-1 · PMID:40451899 · PMC12127465 · W4410936284
article OA: gold CC0 ⤵ 2 in-corpus citations
📄 Open PDF View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Higher adherence to the MIND diet, characterized by nuts, fish, and vegetables, was associated with significantly lower odds of endometriosis in a case-control study.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This hospital-centered case-control study assessed whether adherence to the MIND diet was associated with endometriosis odds in women aged 18–49 in Tehran, Iran, using a validated 168-item food frequency questionnaire and logistic regression adjusted for potential confounders. The analysis included 105 women with gynecologist-confirmed endometriosis and 208 healthy controls, and found that each one-unit increase in MIND diet score was associated with lower endometriosis odds (OR 0.530, 95% CI 0.421–0.666, p<0.001), with high adherence (above the mean) showing even lower odds (OR 0.175, 95% CI 0.080–0.381, p<0.001). Limitations noted include the cross-sectional/case-control design, self-reported dietary intake, and potential unmeasured confounding. This paper is centrally about endometriosis — it evaluates the association between MIND diet adherence (and its component foods) and endometriosis risk.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Endometriosis is a prevalent chronic inflammatory disease in women, which may advantage from potential lifestyle strategies for prevention, modification, or treatment of the condition. The aim of the current study was to evaluate the association between MIND diet and odds of endometriosis. This hospital-centered case-control research, enrolled individuals with endometriosis, diagnosed by a gynecologist, alongside healthy controls, between February to September 2021 in Tehran, Iran. The pattern of diet was assessed utilizing a validated Food Frequency Questionnaire (FFQ) encompassing 168 food items. Logistic regression models were employed to explore the potential connection between MIND diet and the probability of endometriosis. The analysis encompassed 105 subjects with endometriosis and 208 healthy individuals. After adjustment for potential confounders, it was observed that each one-unit increase in the MIND diet score was associated with a 47% lower odds of endometriosis (OR: 0.530; 95% CI: 0.421-0.666, p-value < 0.001). Also, in categorical association, the high adherence to the MIND diet, 83% lower odds of endometriosis were seen in the group by high adherence to the MIND diet (higher than mean), in comparision to the other group (OR: 0.175; 95% CI: 0.080-0.381, p-value < 0.001). Adhering to the MIND diet, rich in healthy components such as nuts, fish and vegetables and lower consumption of inflammatory foods, may potentially reduce the odds of endometriosis. Despite the promising findings, limitations should be considered, including the cross-sectional design, reliance on self-reported dietary intake, and potential unmeasured confounding factors. Further longitudinal studies are needed to confirm these results.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Diet Endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (65)

Cited by (2)

Source provenance

europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pmc
last seen: 2026-05-13T20:22:03.195721+00:00
pubmed
last seen: 2026-06-13T06:19:36.732799+00:00
License: CC0 · commercial use OK