The association of food consumption and nutrient intake with endometriosis risk in Iranian women: A case-control study

Samaneh Youseflu, Youseflu Samaneh, Sadatmahalleh ShahidehJahanian, Shahideh Jahanian Sadatmahalleh, Azadeh Mottaghi, Mottaghi Azadeh, Anoshirvan Kazemnejad, Kazemnejad Anoshirvan
International journal of reproductive biomedicine · 2019 · vol. 17(9) , pp. 661–670 · doi:10.18502/ijrm.v17i9.5102 · PMID:31646261 · W2976009356
article OA: gold CC0 ⤵ 29 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Higher intake of protein, monounsaturated fatty acids, fiber, and specific food groups like vegetables and fruits were associated with a lower risk of endometriosis in Iranian women.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This Iranian case-control study examined associations between dietary intake—specifically food consumption patterns and nutrient intake—and endometriosis risk in women, using reported dietary data from cases and controls. The key finding reported in the paper was that certain aspects of food consumption and nutrient intake were associated with endometriosis risk. A major caveat is that, as a case-control design relying on retrospective dietary assessment, the results are subject to potential recall and selection biases and cannot establish causality. This paper is centrally about endometriosis — it directly analyzes how food consumption and nutrient intake relate to endometriosis risk in Iranian women.

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Abstract

BACKGROUND: Endometriosis, defined as the attendance of endometrial-like lesions in extra uterine locations, causes pain, infertility, and reduced quality of life. OBJECTIVE: To evaluate the relationship between food consumption and nutrient intake with risk of endometriosis. MATERIALS AND METHODS: Of the 156 women approached for the study, 78 women had endometriosis and 78 healthy women were included in the control group. Dietary data were collected using a validated 147-item semi-quantitative Food Frequency Questionnaire (FFQ) with the standard serving size. A logistic regression model was used to determine the association of macronutrients and energy intake with the risk of endometriosis. RESULTS: In women with higher intake of protein, especially animal protein, monounsaturated fatty acids, soluble and insoluble fiber, oleic acid, eicosapentaenoic acid, and docosahexaenoic acid endometriosis is less common (p< 0.05). High consumption of vegetables, fruits, red meat, yellow vegetables, potatoes, legumes, dairy products, liquid oil, and low intake of fried potatoes was associated with a lower risk of endometriosis (p< 0.05). CONCLUSION: Regarding the association of dietary intake on endometriosis risk, counseling about improving the dietary structure can contribute toward the prevention and control of endometriosis.

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endometriosisinfertility

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