The influence of nutrients on the increased risk of developing endometriosis

Anna Zwierzyńska, Jakub Gruszka, Olga Adamczyk-Gruszka
In: Journal of Education, Health and Sport · 2023 · vol. 13(4) , pp. 306–310 · doi:10.12775/jehs.2023.13.04.036 · W4322759275
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This paper examines how nutrient deficiencies and excesses influence endometriosis risk by affecting gene expression and disease susceptibility.

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This paper reviews how nutrient deficiencies and excesses may influence endometriosis risk through mechanisms such as effects on gene expression and epigenetic regulation (narrowly framed as nutrigenomics/early environmental programming). It synthesizes evidence that dietary-related changes can alter susceptibility to disease, with endometriosis discussed alongside broader nutrient–epigenetic–health pathways, and cites prior work on specific nutrients and related biological processes (e.g., oxidative stress and inflammatory pathways). A key limitation is that the paper is not an original study with new patient data, and the mechanistic links are presented across heterogeneous literature rather than tested in a single standardized study. This paper is centrally about endometriosis — focusing on how nutrients and diet-related mechanisms may increase the risk of developing endometriosis.

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Abstract

Diet and nutrition are fundamental to women's health. This condition is affected by both deficiencies and excesses of nutrients. Nutrition affects gene expression, susceptibility to disease through various mechanisms. It affects the expression of genes by changing them, and also affects various diseases, including endometriosis. This disease is quite common and often has a negative impact on women's quality of life.
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The influence of nutrients on the increased risk of developing endometriosis DOI: https://doi.org/10.12775/JEHS.2023.13.04.036Keywords nutrition, gynecological diseases, endometriosis, diet, nutrientsAbstract Diet and nutrition are fundamental to women's health. This condition is affected by both deficiencies and excesses of nutrients. Nutrition affects gene expression, susceptibility to disease through various mechanisms. It affects the expression of genes by changing them, and also affects various diseases, including endometriosis. This disease is quite common and often has a negative impact on women's quality of life. References Izetbegovic, S.; Alajbegovic, J.; Mutevelic, A.; Pasagic, A.; Masic, I. Prevention of diseases in gynecology. Int. J. Prev. Med. 2013, 4, 1347–1358. Kussmann, M.; Fay, L.B. Nutrigenomics and personalized nutrition: Science and concept. Per. Med. 2008, 5, 447–455. [CrossRef] Herceg, Z. 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A randomized exploratory trial to assess the effects of resveratrol on VEGF and TNF-α 2 expression in endometriosis women. J. Reprod. Immunol. 2020, 143, 103248. [CrossRef] Zhou, A.; Hong, Y.; Lv, Y. Sulforaphane attenuates endometriosis in rat models through inhibiting pi3k/akt signaling pathway. Dose Res. 2019, 17, 1559325819855538. [CrossRef] Valipour, J.; Nashtaei, M.S.; Khosravizadeh, Z.; Mahdavinezhad, F.; Nekoonam, S.; Esfandyari, S.; Amidi, F. Effect of sulforaphane on apoptosis, reactive oxygen species and lipids peroxidation of human sperm during cryopreservation. Cryobiology 2021, 99, 122–130. [CrossRef] Stephens, F.B.; Constantin-Teodosiu, D.; Greenhaff, P.L. New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle. J. Pshycol. 2007, 581, 431–444. [CrossRef] Tselekidou, E.D.; Vassiliadis, S.; Athanassakis, I. Establishment or Aggravation of Endometriosis by L-Carnitine: The Role of Pge1 and Pge2 in the Endometriosis-Induction Process. New Developments in Endometriosis. Available online: https: //www.createspace.com Downloads Published How to Cite Issue Section License Copyright (c) 2023 Anna Zwierzyńska, Jakub Gruszka, Olga Adamczyk-Gruszka This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Stats Number of views and downloads: 2745 Number of citations: 0

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