Genetics and infertility II Affected sib-pair analysis in endometriosis

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This paper reviews evidence for a genetic basis of endometriosis and describes the OXEGENE study's use of affected-sib pair analysis to identify susceptibility genes.

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Abstract

This paper (i) reviews the current clinical and molecular genetic data which strongly suggest that endometriosis has a genetic basis; (ii) outlines the general principles of affected-sib pair analysis; and (iii) describes the Oxford Endometriosis Gene (OXEGENE) Study which aims, using a positional cloning approach, to identify susceptibility genes involved in the development of the disease.

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Condition tags

endometriosisinfertility

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (54)

Cited by (12)

Source provenance

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last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK