Genetics and infertility II Affected sib-pair analysis in endometriosis
article
OA: closed
CC0
⤵ 12 in-corpus citations
AI-generated summary
This paper reviews evidence for a genetic basis of endometriosis and describes the OXEGENE study's use of affected-sib pair analysis to identify susceptibility genes.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
This paper (i) reviews the current clinical and molecular genetic data which strongly suggest that endometriosis has a genetic basis; (ii) outlines the general principles of affected-sib pair analysis; and (iii) describes the Oxford Endometriosis Gene (OXEGENE) Study which aims, using a positional cloning approach, to identify susceptibility genes involved in the development of the disease.
My notes (saved in your browser only)
Condition tags
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (54)
- Absence of a relationship between endometriosis and the N314D polymorphism of galactose-1-phosphate uridyl transferase in a UK population via openalex
- Allelotyping of endometriosis with adjacent ovarian carcinoma reveals evidence of a common lineage. via openalex
- Association of estrogen receptor gene polymorphisms with endometriosis via openalex
- Dioxin pollution and endometriosis in Belgium via openalex
- Endometriosis in monozygotic twins via openalex
- Endometriosis in monozygotic twins via openalex
- Endometriosis in Rhesus Monkeys (Macaca mulatta) Following Chronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin via openalex
- Evidence for monoclonal expansion of epithelial cells in ovarian endometrial cysts. via openalex
- Familial inheritance of endometriosis in a British population. A case control study via openalex
- [Genetic aspects of endometriosis: features of the distribution of polymorphic gene frequencies]. via openalex
- Genetic influences on endometriosis in an Australian twin sample via openalex
- Glutathione S-transferase M1 gene polymorphism and susceptibility to endometriosis in a French population via openalex
- GSTM1 null polymorphism and susceptibility to endometriosis and ovarian cancer via openalex
- Heritable aspects of endometriosis via openalex
- Implantation versus Infiltration: The Sampson versus the Endometriotic Disease Theory via openalex
- INCIDENCE OF PELVIC ENDOMETRIOSIS IN ROCHESTER, MINNESOTA, 1970–1979 via openalex
- Magnetic resonance imaging to assess familial risk in relatives of women with endometriosis via openalex
- Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci. via openalex
- Mutation of galactose-1-phosphate uridyl transferase and its association with ovarian cancer and endometriosis via openalex
- Nonpigmented endometriosis: Clinical, laparoscopic, and pathologic definition via openalex
- Possible involvement of arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1 genes in the development of endometriosis via openalex
- Risk factors for endometriosis in the rhesus monkey (Macaca mulatta): a case-control study via openalex
- The genetics of endometriosis via openalex
- W2034957838 via openalex
- W2052330087 via openalex
- W2058569770 via openalex
- W2061941091 via openalex
- W2074891952 via openalex
- W2075734115 via openalex
- W2087184465 via openalex
- W1965265115 via openalex
- W2097999625 via openalex
- W2107871825 via openalex
- W2110604543 via openalex
- W2111067855 via openalex
- W1803375514 via openalex
- W1676452177 via openalex
- W2121876592 via openalex
- W2123466824 via openalex
- W2125391335 via openalex
- W1557101715 via openalex
- W2146888035 via openalex
- W1542836032 via openalex
- W1972563403 via openalex
- W174381814 via openalex
- W1982172757 via openalex
- W1983756554 via openalex
- W1997331575 via openalex
- W1967196243 via openalex
- W2003138212 via openalex
- W2016446596 via openalex
- W2018867449 via openalex
- W2021991929 via openalex
- W2031214502 via openalex
Cited by (12)
- Analysis of Differential Genes of Uyghur Women with Endometriosis in Xinjiang 2012
- Differential Expression of MicroRNAs between Eutopic and Ectopic Endometrium in Ovarian Endometriosis 2010
- Functional genetic polymorphisms and female reproductive disorders: Part II--endometriosis 2008
- Doença tiroideana auto-imune e disfunção tiroideana em mulheres portadoras de endometriose 2007
- What’s the delay? A qualitative study of women’s experiences of reaching a diagnosis of endometriosis 2006
- Induction of endometriosis in the marmoset monkey (Callithrix jacchus) 2006
- Endometriosis: New Genetic Approaches and Therapy 2005
- Genetic Basis of Endometriosis 2004
- Molecular approach to common causes of female infertility 2002
- Avaliação do tempo decorrido entre o inicio dos sintomas e o diagnostico de endometriose 2002
- The Genetic Epidemiology of Spontaneous Endometriosis in the Rhesus Monkey 2002
- Association between endometriosis and N-acetyl transferase 2 polymorphisms in a UK population 2001
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0
· commercial use OK