Adenomyosis and infertility: is there a causal link?

Paolo Vercellini; Irene Bonfanti; Nicola Berlanda

doi:10.1080/17446651.2019.1697675

Adenomyosis and infertility: is there a causal link?

Paolo Vercellini, Irene Bonfanti, Nicola Berlanda

Expert review of endocrinology & metabolism · 2019 · vol. 14(6) , pp. 365–367 · doi:10.1080/17446651.2019.1697675 · PMID:31813292 · W2991610414

editorial OA: bronze CC0 ⤵ 34 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review explores the potential causal link between adenomyosis, a condition where uterine lining tissue grows into the muscle wall, and infertility.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Adenomyosis is a benign uterine disease defined by the presence of endometrial glands and stroma within the myometrium [1,2]. Although about 35% of affected women may be asymptomatic at the time of...

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Condition tags

adenomyosisinfertility

MeSH descriptors

Adenomyosis Infertility Adenomyosis Female Humans Infertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (31)

Adenomyosis: via openalex
Adenomyosis: A reappraisal of symptomatology via openalex
Adenomyosis: A Sonographic Diagnosis via openalex
Adenomyosis does not affect implantation, but is associated with miscarriage in patients undergoing oocyte donation via openalex
Adenomyosis: epidemiological factors via openalex
Adenomyosis has no adverse effects on IVF/ICSI outcomes in women with endometriosis treated with long-term pituitary down-regulation before IVF/ICSI via openalex
Adenomyosis reduces pregnancy rates in infertile women undergoing IVF via openalex
Adenomyosis: Review of the Literature via openalex
An update on adenomyosis in the adolescent via openalex
Asymptomatic adenomyosis and embryo implantation in IVF cycles via openalex
Effect of Adenomyosis on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Infertile Women: A Retrospective Cohort Study via openalex
Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women via openalex
Experimental adenomyosis via openalex
FIGO classification system (PALM‐COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age via openalex
Four subtypes of adenomyosis assessed by magnetic resonance imaging and their specification via openalex
Introduction via openalex
In vitro fertilization and embryo transfer outcomes in relation to myometrial thickness via openalex
Stromal vascularization in the endometrium during adenomyosis via openalex
Structural abnormalities of the uterine wall in women with endometriosis and infertility visualized by vaginal sonography and magnetic resonance imaging via openalex
The effect of adenomyosis on in vitro fertilisation and intra-cytoplasmic sperm injection treatment outcome via openalex
The potential value of magnetic resonance imaging in infertility via openalex
Ultrasound diagnosed adenomyosis has a negative impact on successful implantation following GnRH antagonist IVF treatment via openalex
Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis via openalex
Uterine junctional zone at magnetic resonance imaging: A predictor of <i>in vitro</i> fertilization implantation failure via openalex
Uterotubal transport disorder in adenomyosis and endometriosis—a cause for infertility via openalex
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Cited by (34)

Source provenance

europepmc: last seen: 2026-06-04T01:30:01.192114+00:00
openalex: last seen: 2026-06-04T00:00:01.174412+00:00
pubmed: last seen: 2026-05-13T22:22:22.912744+00:00

License: CC0 · commercial use OK

[1] Adenomyosis: via openalex

[2] Adenomyosis: A reappraisal of symptomatology via openalex

[3] Adenomyosis: A Sonographic Diagnosis via openalex

[4] Adenomyosis does not affect implantation, but is associated with miscarriage in patients undergoing oocyte donation via openalex

[5] Adenomyosis: epidemiological factors via openalex

[6] Adenomyosis has no adverse effects on IVF/ICSI outcomes in women with endometriosis treated with long-term pituitary down-regulation before IVF/ICSI via openalex

[7] Adenomyosis reduces pregnancy rates in infertile women undergoing IVF via openalex

[8] Adenomyosis: Review of the Literature via openalex

[9] An update on adenomyosis in the adolescent via openalex

[10] Asymptomatic adenomyosis and embryo implantation in IVF cycles via openalex

[11] Effect of Adenomyosis on In Vitro Fertilization/Intracytoplasmic Sperm Injection Outcomes in Infertile Women: A Retrospective Cohort Study via openalex

[12] Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women via openalex

[13] Experimental adenomyosis via openalex

[14] FIGO classification system (PALM‐COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age via openalex

[15] Four subtypes of adenomyosis assessed by magnetic resonance imaging and their specification via openalex

[16] Introduction via openalex

[17] In vitro fertilization and embryo transfer outcomes in relation to myometrial thickness via openalex

[18] Stromal vascularization in the endometrium during adenomyosis via openalex

[19] Structural abnormalities of the uterine wall in women with endometriosis and infertility visualized by vaginal sonography and magnetic resonance imaging via openalex

[20] The effect of adenomyosis on in vitro fertilisation and intra-cytoplasmic sperm injection treatment outcome via openalex

[21] The potential value of magnetic resonance imaging in infertility via openalex

[22] Ultrasound diagnosed adenomyosis has a negative impact on successful implantation following GnRH antagonist IVF treatment via openalex

[23] Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis via openalex

[24] Uterine junctional zone at magnetic resonance imaging: A predictor of <i>in vitro</i> fertilization implantation failure via openalex

[25] Uterotubal transport disorder in adenomyosis and endometriosis—a cause for infertility via openalex

[26] W2095024931 via openalex

[27] W2225187239 via openalex

[28] W2753073405 via openalex

[29] W1530237301 via openalex

[30] W2087831276 via openalex

[31] W2133909395 via openalex