Sclerotherapy in the management of ovarian endometrioma: systematic review and meta-analysis

Aviad Cohen, Cohen A, Almog B, Benny Almog, Togas Tulandi, Tulandi T
Fertility and sterility · 2017 · vol. 108(1) , pp. 117–124.e5 · doi:10.1016/j.fertnstert.2017.05.015 · PMID:28579409 · W2621334105
Systematic review / meta-analysis OA: closed CC0 ⤵ 81 in-corpus citations
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This systematic review and meta-analysis examined sclerotherapy as a management option for ovarian endometriomas, assessing its efficacy and safety.

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Abstract

OBJECTIVE: To evaluate the efficacy of sclerotherapy for ovarian endometrioma on the risk of recurrence, clinical symptoms, and reproductive function. DESIGN: Systematic review and meta-analysis. SETTING: Not applicable. PATIENT(S): Patients who underwent sclerotherapy of ovarian endometrioma. INTERVENTION(S): An electronic-based search with the use of Pubmed, Embase, Ovid Medline, Google Scholar, Clinicaltrials.gov, and the Cochrane Central Register of Controlled Trials. MAIN OUTCOME MEASURE(S): Recurrence rate, symptoms relief, fertility outcome, and adverse events. RESULT(S): Eighteen studies were included in our review. The overall recurrence rates of endometrioma after sclerotherapy ranged from 0 to 62.5%. The risk of recurrence was significantly higher in women who were treated by means of ethanol washing than by means of ethanol retention. The number of oocytes retrieved was higher after endometrioma sclerotherapy compared with laparoscopic cystectomy, but clinical pregnancy rates were similar. There was no difference in the number of oocytes retrieved and the clinical pregnancy rates between the sclerotherapy-treated group with and the untreated group. CONCLUSION(S): Sclerotherapy for ovarian endometrioma may be considered in symptomatic women who plan to conceive.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Endometriosis Infertility, Female Infertility, Female Pregnancy Outcome Sclerotherapy Adolescent Adolescent Adult Adult Endometriosis Endometriosis Female Female Humans Humans Infertility, Female Infertility, Female Middle Aged Middle Aged

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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Cited by (50)

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