Safety and Clinical Outcomes of Two-Session Catheter-Directed Sclerotherapy Using Ethanol for Endometrioma

Chu Hui Zeng, Chuan Wu Cao, Ji Hoon Shin, Gun Ha Kim, Sung Hoon Kim, Sa Ra Lee, Shin Wha Lee, Shin‐Wha Lee
Cardiovascular and interventional radiology · 2024 · vol. 47(7) , pp. 901–909 · doi:10.1007/s00270-024-03700-5 · PMID:38528174 · W4393179154
article OA: closed CC0 ⤵ 4 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Two-session catheter-directed sclerotherapy with ethanol effectively reduced endometrioma volume, with minor complications and preserved ovarian function.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This prospective study evaluated the safety and clinical outcomes of two-session catheter-directed sclerotherapy using 99% ethanol in patients with ovarian endometrioma, treating 31 endometriomas in 22 consecutive patients via transvaginal ultrasound-guided aspiration followed by ethanol injection with catheter retention for a second session the next day. Endometrioma size was assessed by ultrasound at baseline and 1, 3, and 6 months, and serum anti-Müllerian hormone (AMH) was measured before and 6 months after to assess ovarian reserve. Minor procedure-related complications occurred in four patients and resolved before discharge; treatment was incomplete in three endometriomas due to contrast leakage or pain, and no recurrence was identified during follow-up. Although mean endometrioma diameter and volume reduction improved substantially, AMH decreased without statistical significance, and the paper’s main limitation is that it reports outcomes without identifying a longer-term recurrence and includes a relatively small single-arm sample. This paper is centrally about endometriosis — it specifically evaluates two-session ethanol catheter-directed sclerotherapy for ovarian endometrioma.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Ethanol Ethanol Ethanol Ethanol Ethanol Ethanol Ethanol Ethanol

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References (40)

Cited by (4)

SciLite annotations

chemicals 4
ethanol ethanol ethanol ethanol

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europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
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pubmed
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License: CC0 · commercial use OK