The Local Immune Mechanisms Involved in the Formation of Endometriotic Lesions

Yulia S. Antsiferova, Natalya Sotnikov
In: Endometriosis - Basic Concepts and Current Research Trends · 2012 · doi:10.5772/29965 · W1577826334
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This paper explores the role of the immune system in the growth of ectopic endometrial-like tissue characteristic of endometriosis, viewing the condition as an autotransplant.

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Abstract

According to common view, endometriosis is characterized by the presence and growth of the endometrium-like glandular tissue and stroma outside the uterus. So, endometriosis would represent an autotransplant in which tissue is transplanted to an ectopic location in an organism. It is well known that the immune system plays the main role in regulation of tissue homeostasis in an organism. Thus, immunologists have a special interest in this disease as insights in the pathogenesis of endometriosis would help not only to understand how ectopic lesions grow but also allow searching new approaches to the medical treatment of this disease.

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endometriosis

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