Endometrioid stromal sarcomas arising from ovarian and extraovarian endometriosis: Report of two cases and review of the literature

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AI-generated summary by claude@2026-06, 2026-06-09

This report details two cases of endometrioid stromal sarcomas originating from endometriosis in the ovary and outside the ovary, alongside a review of existing literature.

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Abstract

Endometrioid stromal sarcomas arising from endometriosis are rare tumors. Two cases from our institution are presented and the literature is reviewed. The patients tend to be nulliparous. Presentations usually are related to the symptoms of a pelvic mass. However, extraovarian origin was frequently accompanied by hemorrhage. The tumors are usually of low histologic grade. Among 18 patients with ovarian origin, only 2 were reported dead of disease. However, 5 of 13 patients with extraovarian origin died mostly as a result of recurrent disease. Deaths generally occurred within 3 years of diagnosis. The efficacy of chemotherapy, radiotherapy, or hormonal therapy in the adjuvant or recurrent setting cannot be determined from the available reports.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Neoplasms Sarcoma Uterine Neoplasms Adult Endometriosis Endometriosis Female Humans Middle Aged Ovarian Neoplasms Sarcoma Sarcoma Uterine Neoplasms Uterine Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (29)

Cited by (36)

Source provenance

europepmc
last seen: 2026-07-25T06:15:30.875455+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:12:15.619952+00:00
License: CC0 · commercial use OK