Endometrial stromal sarcoma arising from vaginal endometriosis.

In: PubMed · 1978 · vol. 51(1 Suppl) , pp. 34s–37s · W2395908535
article OA: closed CC0 ⤵ 24 in-corpus citations
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AI-generated summary by claude@2026-06, 2026-06-09

This case reports vaginal endometriosis with endometrial stromal sarcoma and high-dose estrogen, prompting investigation into estrogen's role in malignant transformation.

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Abstract

The present case reports the concurrence of endometriosis of the vaginal cuff with endometrial stromal sarcoma in association with high-dose estrogen. This case raises the question of whether chronic high-dose estrogen might be associated with malignant transformation of endometrial stroma. Although there is no definitive evidence of a causal relation between estrogen and endometrial stromal sarcoma, the possibility should be explored further. Therapy of this neoplasm is discussed and salient clinical and pathologic features are reviewed.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (24)

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last seen: 2026-06-04T00:00:01.174412+00:00
License: CC0 · commercial use OK