Vaginal endometrial stromal sarcoma: A literature review

Hongwen Wu, Yi Luo, Nanlin Yin, Wenwu Gui, Yi Cao
European journal of obstetrics & gynecology and reproductive biology: X · 2019 · vol. 4 , pp. 100094 · doi:10.1016/j.eurox.2019.100094 · PMID:31528854 · PMC6742903 · W2970706871
review OA: gold CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This literature review of 13 VESS cases indicates it is a rare disease potentially linked to endometriosis, diagnosed pathologically, and treated with multimodal therapy, with prognosis influenced by stage and hormonal receptor expression.

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Abstract

Vaginal endometrial stromal sarcoma (VESS) is a rare disease. To the best of our knowledge, there have only been a few reported cases in the literature. Therefore, we conducted a literature review to obtain specific knowledge of this disease. Thirteen cases of VESS were found by searching the Medline and EMBASE databases in the English language. The mechanism of VESS may be associated with endometriosis, and its diagnosis largely depends on pathological examination because it has no typical symptoms. Treatment of VESS incorporates surgery, chemotherapy, radiotherapy, and hormonal therapy. Some novel drugs targeting its mechanism may become alternative therapies. Its prognostic factors may include tumor stage and the expression of hormonal receptors.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (36)

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europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
openalex
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pubmed
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