Low-grade endometrial stromal sarcoma presenting as vaginal nodule

Corpa MV, Marcus V N Corpa, Eduardo Pretto Serafini, Eduardo P Serafini, Serafini EP, Bacchi CE, Carlos E Bacchi
Annals of diagnostic pathology · 2004 · vol. 8(5) , pp. 295–298 · doi:10.1016/j.anndiagpath.2004.07.007 · PMID:15494937 · W2092686768
article OA: closed CC0 ⤵ 9 in-corpus citations
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This case report describes a rare instance of low-grade endometrial stromal sarcoma manifesting as a vaginal nodule, highlighting an unusual presentation for this type of malignancy.

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Abstract

Endometrial stromal sarcoma is a rare neoplasm of the uterus. Extrauterine locations of this neoplasm, excluding metastases or local extension, are even more unusual and are usually associated with the presence of endometriosis. The authors report a case of endometrial stromal sarcoma presenting as a vaginal wall nodule, without any sign of primary uterine tumor after extensive evaluation or presence of endometriosis. The morphology, immunohistochemical profile, differential diagnoses, and pathogenesis are discussed, as well as a review of the literature on this issue.

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MeSH descriptors

Endometrial Neoplasms Sarcoma, Endometrial Stromal Vaginal Neoplasms Adult Antigens, CD Antigens, CD Biomarkers, Tumor Biomarkers, Tumor Diagnosis, Differential Disease-Free Survival Endometrial Neoplasms Endometrial Neoplasms Endometrial Neoplasms Female Humans Immunohistochemistry Receptors, Estrogen Receptors, Estrogen Receptors, Progesterone Receptors, Progesterone

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