Low-grade endometrial stromal sarcoma presenting as vaginal nodule
Case report
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⤵ 9 in-corpus citations
AI-generated summary
This case report describes a rare instance of low-grade endometrial stromal sarcoma manifesting as a vaginal nodule, highlighting an unusual presentation for this type of malignancy.
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Abstract
Endometrial stromal sarcoma is a rare neoplasm of the uterus. Extrauterine locations of this neoplasm, excluding metastases or local extension, are even more unusual and are usually associated with the presence of endometriosis. The authors report a case of endometrial stromal sarcoma presenting as a vaginal wall nodule, without any sign of primary uterine tumor after extensive evaluation or presence of endometriosis. The morphology, immunohistochemical profile, differential diagnoses, and pathogenesis are discussed, as well as a review of the literature on this issue.
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References (27)
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Cited by (9)
- Low-grade extrauterine endometrial stromal sarcoma arising from vaginal endometriosis: a case report and literature review 2023
- Vaginal endometrial stromal sarcoma: A literature review 2019
- Fertility-Sparing Surgery for Patients with Endometrioid Stromal Sarcoma of Ovary: A Case Report with a Review of the Literature 2018
- Primary extragenital endometrial stromal sarcoma of the lung: first reported case and review of literature 2017
- A Rare Case of Multiple Malignancies arising in Endometriosis: Diffuse Extra-Uterine High-grade Endometrial Stromal Sarcoma and Ovarian Carcinoma 2015
- Endometrial stromal nodule of the vaginal wall with a review of vulvovaginal endometrial stromal neoplasms 2014
- Endometrial stromal sarcoma arising from endometriosis of the terminal ileum: the role of immunohistochemistry in the differential diagnosis 2012
- Extragenital endometrial stromal sarcoma arising in endometriosis 2012
- Endometrial stromal sarcoma of the small bowel 2008
Source provenance
- europepmc
- last seen: 2026-10-10T06:11:15.153948+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-10-08T21:02:47.667321+00:00
License: CC0
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