Stromal sarcoma arising on endometriosis. A clinicopathological and immunohistochemical study of 4 cases.

A Kondi-Paphitis, B Smyrniotis, A Liapis, Angelos Liapis, A Kontoyanni, H Deligeorgi
European journal of gynaecological oncology · 1998 · vol. 19(6) , pp. 588–90 · PMID:10215449 · W2415680146
article OA: closed CC0 ⤵ 13 in-corpus citations
View on OpenAlex View on PubMed
⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

This study investigated four cases of endometrial stromal sarcoma arising on endometriosis, characterizing them immunophenotypically and pathologically to aid in differential diagnosis and treatment.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

The development of stromal sarcomas on the foci of endometriosis is extremely rare and the differential diagnosis from other tumors of myogenic, vascular, hemopoietic or epithelial origin may present great diagnostic difficulties. We investigated the clinicopathological and immunohistochemical characteristics of 4 cases of endometrial stromal sarcoma that developed on endometriotic foci of the uterus, vagina and omentum. Thye were classed as high grade (1/4) or low grade (3/4) malignant potential tumors, according to their mitotic activity. Immunohistochemically these tumors gave a positive reaction to vimentin, but were negative to desmin, smooth muscle actin, factor VIII, EMA and LCA. These characteristics permit their identification and a proper therapeutic approach.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometrial Neoplasms Endometriosis Omentum Peritoneal Neoplasms Sarcoma, Endometrial Stromal Uterine Neoplasms Vaginal Neoplasms Biopsy, Needle Diagnosis, Differential Disease-Free Survival Endometrial Neoplasms Endometrial Neoplasms Endometrial Neoplasms Endometriosis Endometriosis Female Humans Immunohistochemistry Middle Aged Omentum

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (13)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:10:35.327253+00:00
License: CC0 · commercial use OK