RATIONALE: Adenomyosis is a common uterine disorder, yet its aetiology remains debated. The tissue injury and repair (TIAR) hypothesis suggests that repeated microtrauma from menstrual contractions damages the endometrial-myometrial interfa…
OBJECTIVE: The risk factors for the postoperative recurrence of cellular uterine leiomyoma (CUL) remain unclear.This study aimed to identify independent risk factors for recurrence and to develop a predictive model based on clinical charact…
OBJECTIVE: To evaluate the clinical efficacy and safety of a novel hysteroscopic myomectomy technique, RoBEEM (Roller ball Enucleation followed by Excision Method), developed to expand the indications of transcervical resection of myomas (T…
This case report describes the complete excision of a parasitic fibroid using the vaginal natural orifice transluminal endoscopic surgery (vNOTES) technique in a 49-year-old morbidly obese female patient. The patient presented with heavy me…
INTRODUCTION: Deep infiltrating endometriosis (DIE) is associated with substantial impairment in health-related quality of life (HRQoL), affecting pain, emotional well-being, sexual functioning, and daily activities. Previous studies have s…
OBJECTIVE: To evaluate the live birth rate (LBR) of assisted reproductive technology (ART) treatment using vitrified donated oocytes in China and to investigate the influencing factors on live birth outcomes. METHODS: This retrospective co…
Recurrent implantation failure (RIF) is among the biggest problems in assisted reproductive treatments. Recently, there is a suggestion of intrauterine injection of platelet-rich plasma (PRP) as a novel method of enhancing endometrial recep…
BACKGROUND: Endometriosis is benign, but it is associated with an increased risk of clear-cell and endometrioid ovarian carcinoma. Several multivariable prediction models have been developed to identify malignant transformation or different…
BACKGROUND: The GnRH antagonist protocol is widely used in IVF/ICSI treatments. It involves daily injections of a GnRH antagonist starting on stimulation day 5 or later to prevent premature ovulation by suppressing the endogenous gonadotrop…
OBJECTIVE: To evaluate the real-world effectiveness, safety, and tolerability of relugolix/estradiol/norethisterone acetate combination therapy (relugolix CT) for managing symptomatic uterine fibroids in routine gynaecological practice. ME…
OBJECTIVE: To identify risk factors for dispensed opioid prescriptions after benign hysterectomy. DESIGN: A nationwide register-based cohort study including 50,601 hysterectomies with complete data from the Swedish National Quality Registe…
BACKGROUND: Postoperative pelvic pain is a clinically relevant outcome after laparoscopic hysterectomy with ovarian preservation. Hyaluronic acid barriers can reduce postoperative adhesion formation, but whether this translates into lower l…
OBJECTIVE: This study describes the examination procedure and clinical outcomes of hysterosalpingo-contrast sonography (HyCoSy) with perflubutane used as the ultrasound contrast agent for tubal patency evaluation. METHODS: Infertile women …
Gedeon Richter and Ferring Pharmaceuticals; Gedeon-Richter; Samsung
OBJECTIVE: To compare the risk of opioid use, antimicrobial utilization, and postoperative complications, including paralytic ileus, between patients undergoing abdominal hysterectomy and sacrocolpopexy. METHODS: Using a global federated h…
INTRODUCTION: The anti-inflammatory nature of curcumin suggests its potential to modulate the body's inflammatory processes, offering a novel avenue for mitigating heightened inflammatory responses often observed in conditions like PMS and …
OBJECTIVE: Recurrent implantation failure (RIF) is a clinical phenomenon characterized by a lack of implantation after several embryo-transfers. The aim of this study was to evaluate missing pelvic pathologies in patients with RIF, followin…
INTRODUCTION: Uterine scar defects result from poor healing of the hysterotomy after cesarean sections (CS), in multiple cases leading to retroflexio uteri and retrograde menstruation. Endometriosis is the probable consequence. Patients oft…
Focused ultrasound (FUS) appears to be a promising form of thermal ablation for treatment of cervical lesions, but evidence supporting its use is limited. This review evaluated the efficacy and safety of FUS treatment of cervical human papi…
BACKGROUND: The present study was conducted to evaluate the efficacy of curcumin capsules on the severity and duration of primary dysmenorrhea. METHODS: A randomized controlled trial conducted among female students at Hamadan University of…
OBJECTIVE: Vaginal natural orifice transluminal endoscopy (vNOTES) is a minimally invasive technique gaining popularity for several gynaecological procedures. This study presents the first 81 adnexal cases, performed in The Netherlands. DE…
OBJECTIVE: Women are often concerned about the absolute quantity and quality of sperm in a thawed donor sample at the time of intrauterine insemination (IUI). The aim of this study was to determine how the total motile sperm count (TMSC) of…
Selecting an appropriate oral contraceptive can be challenging for healthcare professionals due to the abundance of marketed contraceptive options with different clinical and real-world effectiveness and safety profiles. Nomegestrol acetate…
OBJECTIVE: This study aims to analyze giant ovarian tumors' clinical and pathological characteristics. MATERIAL AND METHODS: This was an analytical observational study. Medical records of all patients with giant ovarian tumors who underwen…