European journal of obstetrics & gynecology and reproductive biology: X

RATIONALE: Adenomyosis is a common uterine disorder, yet its aetiology remains debated. The tissue injury and repair (TIAR) hypothesis suggests that repeated microtrauma from menstrual contractions damages the endometrial-myometrial interfa…

OBJECTIVE: The risk factors for the postoperative recurrence of cellular uterine leiomyoma (CUL) remain unclear.This study aimed to identify independent risk factors for recurrence and to develop a predictive model based on clinical charact…

This case report describes the complete excision of a parasitic fibroid using the vaginal natural orifice transluminal endoscopic surgery (vNOTES) technique in a 49-year-old morbidly obese female patient. The patient presented with heavy me…

BackgroundThe GnRH antagonist protocol is widely used in IVF/ICSI treatments. It involves daily injections of a GnRH antagonist starting on stimulation day 5 or later to prevent premature ovulation by suppressing the endogenous gonadotropin…

ObjectiveTo evaluate the real-world effectiveness, safety, and tolerability of relugolix/estradiol/norethisterone acetate combination therapy (relugolix CT) for managing symptomatic uterine fibroids in routine gynaecological practice.Method…

OBJECTIVE: To identify risk factors for dispensed opioid prescriptions after benign hysterectomy. DESIGN: A nationwide register-based cohort study including 50,601 hysterectomies with complete data from the Swedish National Quality Registe…

Gedeon Richter and Ferring Pharmaceuticals; Gedeon-Richter; Samsung

ObjectiveTo compare the risk of opioid use, antimicrobial utilization, and postoperative complications, including paralytic ileus, between patients undergoing abdominal hysterectomy and sacrocolpopexy.MethodsUsing a global federated health …

IntroductionThe anti-inflammatory nature of curcumin suggests its potential to modulate the body's inflammatory processes, offering a novel avenue for mitigating heightened inflammatory responses often observed in conditions like PMS and dy…

OBJECTIVE: Recurrent implantation failure (RIF) is a clinical phenomenon characterized by a lack of implantation after several embryo-transfers. The aim of this study was to evaluate missing pelvic pathologies in patients with RIF, followin…

INTRODUCTION: Uterine scar defects result from poor healing of the hysterotomy after cesarean sections (CS), in multiple cases leading to retroflexio uteri and retrograde menstruation. Endometriosis is the probable consequence. Patients oft…

Focused ultrasound (FUS) appears to be a promising form of thermal ablation for treatment of cervical lesions, but evidence supporting its use is limited. This review evaluated the efficacy and safety of FUS treatment of cervical human papi…

BackgroundThe present study was conducted to evaluate the efficacy of curcumin capsules on the severity and duration of primary dysmenorrhea.MethodsA randomized controlled trial conducted among female students at Hamadan University of Medic…

ObjectiveVaginal natural orifice transluminal endoscopy (vNOTES) is a minimally invasive technique gaining popularity for several gynaecological procedures. This study presents the first 81 adnexal cases, performed in The Netherlands.Design…

ObjectiveWomen are often concerned about the absolute quantity and quality of sperm in a thawed donor sample at the time of intrauterine insemination (IUI). The aim of this study was to determine how the total motile sperm count (TMSC) of d…

Selecting an appropriate oral contraceptive can be challenging for healthcare professionals due to the abundance of marketed contraceptive options with different clinical and real-world effectiveness and safety profiles. Nomegestrol acetate…

ObjectiveThis study aims to analyze giant ovarian tumors' clinical and pathological characteristics.Material and methodsThis was an analytical observational study. Medical records of all patients with giant ovarian tumors who underwent surg…

ObjectiveBariatric surgery has an impact on subsequent pregnancies, in particular an association between gastric bypass and small for gestational age. Knowledge is lacking on whether sleeve gastrectomy is associated with more favorable preg…

Objective: To determine the efficacy and safety of rectal diclofenac for relieving postoperative pain following diagnostic hystero-laparoscopy and dye test (dHLD). Methods: A prospective, double-blind, placebo-controlled, randomized trial w…

INTRODUCTION: This study aimed to analyze the worldwide, regional burden of endometriosis and its trends from 1990 to 2019, utilizing the latest data from Global Burden of Disease (GBD) 2019. GBD 2019 is a global database tool for comprehen…

Intramural pregnancies (IMP) are very rare and represent about 1% of ectopic pregnancies (EPs). Despite a few reported cases, there is limited awareness & knowledge among sonographers and physicians. Moreover, no established diagnostic or t…

PURPOSE: We aimed to examine the clinical characteristics of patients with ovarian endometriosis (OMA) who were diagnosed with recurrent pain after laparoscopic surgery in an 8- to 12- year postoperative follow-up. METHODS: We retrospectiv…

ObjectiveEach repeat cesarean section (CS) potentially adds surgical complexity. The determination of appropriate anesthesia strategy to meet the surgical challenge is of crucial importance for the maternal and neonatal outcome.Study design…

ObjectiveThis study aims to evaluate the correlation and diagnostic value of maternal serum placental markers: pregnancy-associated plasma protein-A (PAPP-A), free beta human chorionic gonadotropin (free β-hCG), and alpha fetoprotein (AFP) …