Malignant transformation of vaginal endometriosis
Case report
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⤵ 25 in-corpus citations
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This case report documents the malignant transformation of vaginal endometriosis over a 13-year period, coinciding with exogenous estrogen replacement.
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Abstract
A well-documented case of extraovarian endometriosis undergoing malignant transformation is presented. A vaginal focus of endometriosis was biopsied over a 13-year interval during which time progression from benign to malignant disease was observed. Exogenous estrogen replacement was administered throughout the interval of transformation. The pathology, pertinent literature, and implications of the present case are discussed.
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Cited by (24)
- Vaginal stump endometriosis following total laparoscopic hysterectomy: A case report 2022
- Malignant Transformation of Postmenopausal Endometriosis: A Systematic Review of the Literature 2021
- A Locally Advanced Endometrioid Adenocarcinoma Arising from Vaginal Endometriosis: Management and Review of the Literature 2021
- Malignant Transformation of Vaginal Endometriosis - A Review of Literature 2016
- A Case of Clear Cell Adenocarcinoma Arising in the Endometriosis of the Rectum 2009
- Hormone replacement therapy in women with past history of endometriosis 2006
- Malignant extraovarian endometriosis: a review 2005
- An unusual rectosigmoid mass: endometrioid adenocarcinoma arising in colonic endometriosis: case report and literature review 2005
- [Endometrioid adenocarcinoma arising from adenomyosis. A case report and literature review] 2004
- Vaginal vault endometriosis de novo, associated with hormone replacement therapy 2004
- Atypical epithelial changes and mutant p53 gene expression in ovarian endometriosis 2001
- Endometrioid adenocarcinoma arising from adenomyosis 1999
- Malignancies arising in endometriosis 1999
- Adenocarcinoma arising in extragonadal endometriosis: an immunohistochemical study 1998
- Extraovarian endometrioid carcinoma associated with unopposed oestrogen replacement therapy 1998
- Malignant tumors arising in endometriosis: clinical-pathological study and flow cytometry analysis 1996
- A CASE OF MALIGNANT MIXED EPITHELIAL TUMOR ARISING FROM ENDOMETRIOSIS OF THE RECTOVAGINAL SEPTUM 1996
- Endometriosis and atypical complex hyperplasia associated with unopposed oestrogen therapy 1994
- Management of endometriosis in women older than 40 years of age 1993
- The role of definitive surgery and hormone replacement therapy in the treatment of endometriosis 1991
- Clear cell carcinoma of the inguinal region arising from endometriosis 1991
- Vaginal endometrioid adenocarcinoma arising in vaginal endometriosis: a case report and literature review 1989
- Vaginal adenocarcinoma developing in residual pelvic endometriosis: a clinical dilemma 1989
- Endometriosis, Lesions of the Secondary Müllerian System, and Pelvic Mesothelial Proliferations 1987
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- europepmc
- last seen: 2026-10-13T06:10:10.580696+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:58:15.129929+00:00
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