Vaginal stump endometriosis following total laparoscopic hysterectomy: A case report

In: JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY · 2022 · vol. 38(2) , pp. 235–239 · doi:10.5180/jsgoe.38.2_235 · W4317924364
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This case report describes a 40-year-old woman diagnosed with vaginal stump endometriosis presenting with genital bleeding nine months after total laparoscopic hysterectomy.

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This paper reports a 40-year-old nulliparous patient who underwent total laparoscopic hysterectomy with bilateral salpingectomy for uterine leiomyomas and had a small ~1 cm endometriotic lesion with partial adhesions in the Douglas pouch at surgery, while the resected uterus showed leiomyoma without adnexal endometriosis. The patient developed periodic genital bleeding at 2 and 5 months postoperatively and later genital bleeding with periumbilical pain at 9 months; colposcopy then showed multiple red endometriosis-like lesions involving the vaginal stump, leading to a diagnosis of vaginal stump endometriosis. The authors note a key limitation that preoperative identification of small lesions in the Douglas pouch is difficult when imaging does not reveal endometriosis elsewhere, and that even mild pelvic endometriosis can leave lesions in the vaginal stump. This paper is centrally about endometriosis — vaginal stump endometriosis after total laparoscopic hysterectomy.

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Abstract

A 40-year-old G0P0 presented with uterine leiomyomas and underwent total laparoscopic hysterectomy and bilateral salpingectomy for management of worsening hypermenorrhea. Intraperitoneal findings included an endometriotic lesion (approximately 1 cm) in the peritoneum of the Douglas pouch and partial adhesion. The vaginal canal was incised, and the uterus was transected and removed after transvaginal morcellation. Histopathological examination of the resected specimen revealed uterine leiomyoma without salpingeal abnormalities or endometriotic lesions. The patient observed monthly genital bleeding, 2 and 5 months postoperatively; however, no apparent clinical abnormalities were detected. She experienced similar genital bleeding accompanied by periumbilical pain, 9 months postoperatively. Colposcopy revealed several red endometriosis-like lesions involving the vaginal stump, and the patient was diagnosed with vaginal stump endometriosis. Oral dienogest administration initiated at 11 months postoperatively was continued as maintenance therapy, and the patient's symptoms nearly resolved 5 months later.
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症例報告 全腹腔鏡下子宮全摘出後に生じた腟断端子宮内膜症の1例 2022 年 38 巻 2 号 p. 235-239 詳細 抄録 A 40-year-old G0P0 presented with uterine leiomyomas and underwent total laparoscopic hysterectomy and bilateral salpingectomy for management of worsening hypermenorrhea. Intraperitoneal findings included an endometriotic lesion (approximately 1 cm) in the peritoneum of the Douglas pouch and partial adhesion. The vaginal canal was incised, and the uterus was transected and removed after transvaginal morcellation. Histopathological examination of the resected specimen revealed uterine leiomyoma without salpingeal abnormalities or endometriotic lesions. The patient observed monthly genital bleeding, 2 and 5 months postoperatively; however, no apparent clinical abnormalities were detected. She experienced similar genital bleeding accompanied by periumbilical pain, 9 months postoperatively. Colposcopy revealed several red endometriosis-like lesions involving the vaginal stump, and the patient was diagnosed with vaginal stump endometriosis. Oral dienogest administration initiated at 11 months postoperatively was continued as maintenance therapy, and the patient's symptoms nearly resolved 5 months later. Preoperative diagnosis of small lesions in the Douglas pouch is challenging in patients in whom imaging does not reveal endometriosis in any other region. Endometriotic lesions may remain in the vaginal stump, even in the absence of uterine or adnexal endometriosis, and such lesions may occur even in patients with mild pelvic endometriosis. Vaginal stump endometriosis should be considered in the differential diagnosis in women with periodic genital bleeding or abdominal pain after total laparoscopic hysterectomy. Detailed patient interviews and physical evaluation within a wide area are necessary. Vaginal stump endometriosis can be histopathologically diagnosed based on biopsy specimen evaluation, and dienogest therapy is useful for symptom relief. © 2022 日本産科婦人科内視鏡学会

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