A Case of Clear Cell Adenocarcinoma Arising in the Endometriosis of the Rectum

Shigenori Homma, Akihiko Kataoka, Norihiko Takahasi, Hideyasu Sakihama, Ayami Sasaki, Satoru Todo
In: Nippon Daicho Komonbyo Gakkai Zasshi · 2009 · vol. 62(6) , pp. 416–419 · doi:10.3862/jcoloproctology.62.416 · W2082785660
Case report OA: hybrid CC0 ⤵ 1 in-corpus citation
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-18 ⓘ

This case report describes a 50-year-old woman diagnosed with clear cell adenocarcinoma arising in rectal endometriosis, treated with low anterior resection and hysterectomy, followed by chemotherapy.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by qwen3.7-flash, 2026-09-01 · read from full text ⓘ

This case report describes a 50-year-old woman who presented with hematochezia and abdominal pain, leading to the diagnosis of poorly differentiated adenocarcinoma in the rectum. Surgical intervention involved low anterior resection and total hysterectomy with bilateral adnexectomy, revealing that the tumor was a clear cell adenocarcinoma arising from ectopic endometriosis within the rectal wall. The patient received chemotherapy similar to that for ovarian cancer following surgery due to advanced staging and lymph node involvement. This paper is centrally about endometriosis — specifically the malignant transformation of deep infiltrating endometriosis in the rectum into clear cell adenocarcinoma.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

症例は50歳代の女性で2007年10月に血便と腹痛を主訴に近医を受診し，直腸癌の診断で2008年1月当科入院となった．既往歴で2005年6月に右乳癌で乳房円状部分切除を行い，術後放射線治療とアロマターゼ阻害薬の内服治療をおこなった．下部消化管内視鏡検査で肛門縁より12cmの直腸に亜全周性の2型腫瘍を認めた．生検では低分化腺癌であった．CTでは直腸に造影効果のある腫瘤性病変を認め，子宮とは一部不明瞭で浸潤が疑われた．2008年1月に低位前方切除，単純子宮全摘術，両側付属器切除を行った．病理組織検査で直腸の異所性子宮内膜症を発生母体とした明細胞腺癌と診断された．Ra，2型，4.5×2.5cm，clear cell adenocarcinoma，pSS，int，INF b，ly2，v1，pN2（7/36），pStage IIIbであった．術後に卵巣癌に準じた化学療法（PTX/CBDCA）を婦人科で行っている．異所性子宮内膜症を発生母体とする直腸原発明細胞腺癌の1例を経験した．
Full text 641 characters · extracted from oa-doi-fallback · click to expand
症例報告 異所性子宮内膜症を発生母体とする直腸明細胞腺癌の1例 2009 年 62 巻 6 号 p. 416-419 詳細 抄録 症例は50歳代の女性で2007年10月に血便と腹痛を主訴に近医を受診し，直腸癌の診断で2008年1月当科入院となった．既往歴で2005年6月に右乳癌で乳房円状部分切除を行い，術後放射線治療とアロマターゼ阻害薬の内服治療をおこなった．下部消化管内視鏡検査で肛門縁より12cmの直腸に亜全周性の2型腫瘍を認めた．生検では低分化腺癌であった．CTでは直腸に造影効果のある腫瘤性病変を認め，子宮とは一部不明瞭で浸潤が疑われた．2008年1月に低位前方切除，単純子宮全摘術，両側付属器切除を行った．病理組織検査で直腸の異所性子宮内膜症を発生母体とした明細胞腺癌と診断された．Ra，2型，4.5×2.5cm，clear cell adenocarcinoma，pSS，int，INF b，ly2，v1，pN2（7/36），pStage IIIbであった．術後に卵巣癌に準じた化学療法（PTX/CBDCA）を婦人科で行っている．異所性子宮内膜症を発生母体とする直腸原発明細胞腺癌の1例を経験した． © 2009 日本大腸肛門病学会 この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (11)

Cited by (1)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK