Proton irradiation and endometriosis
Lab / animal
OA: closed
CC0
⤵ 37 in-corpus citations
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Female monkeys exposed to proton irradiation at doses and energies comparable to those from a solar flare developed endometriosis significantly more often than unexposed animals.
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Abstract
Female rhesus monkeys given single total-body exposures of protons of varying energies developed endometriosis at a frequency significantly higher than that of nonirradiated animals of the same age. The minimum latency period was 7 years after exposure. The doses and energies of the radiation received were within the range that could be received by an aircrew member in near-earth orbit during a random solar flare event, leading to the conclusion that endometriosis should be a consideration in assessing the risk of delayed radiation effects in female crewmembers.
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Cited by (37)
- Deep Infiltrating Endometriosis in Adolescence: Early Diagnosis and Possible Prevention of Disease Progression 2024
- The Genetic-Epigenetic Pathophysiology of Endometriosis: A Surgeon’s View 2020
- Pathogenesis of endometriosis: the genetic/epigenetic theory 2018
- Altered Immunity in Endometriosis: What Came First? 2018
- Endometriosis 2015
- Role of Environmental Pollutants in Endometriosis 2015
- Immunological aspects of endometriosis: a review 2015
- Air pollution exposures during adulthood and risk of endometriosis in the Nurses' Health Study II 2013
- Primate model research for endometriosis 2012
- Endometriosis 2010
- The link between environmental toxicant exposure and endometriosis 2007
- The link between exposure to dioxin and endometriosis: a critical reappraisal of primate data 2004
- Immunology of endometriosis 2004
- Ultrasound Characteristics of Endometriosis 2003
- The genetic epidemiology of spontaneous endometriosis in the rhesus monkey 2002
- Dioxins and endometriosis: a plausible hypothesis 2002
- Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium 2001
- Expression of AhR and ARNT mRNA in cultured human endometrial explants exposed to TCDD 2001
- Serum levels of TCDD and dioxin-like chemicals in Rhesus monkeys chronically exposed to dioxin: correlation of increased serum PCB levels with endometriosis 2001
- Chlorinated hydrocarbons in infertile women 1999
- The physiopathology of endometriosis: pollution and dioxin 1999
- Pathogenesis of endometriosis: the role of peritoneal fluid 1999
- Endometriotic disease: the role of peritoneal fluid 1998
- Risk factors for endometriosis in the rhesus monkey (Macaca mulatta): a case-control study 1997
- Immunological aspects of endometriosis 1996
- Prevalence of Endometriosis in Rhesus (<i>Macaca mulatta</i>) Monkeys Ingesting PCB (Aroclor 1254): Review and Evaluation 1996
- Identification of rhesus macaques with spontaneous endometriosis 1996
- Prevalence of endometriosis in rhesus (Macaca mulatta) monkeys ingesting PCB (Aroclor 1254): review and evaluation 1996
- Immunological aspects of endometriosis 1995
- Immunoresponsiveness in Endometriosis: Implications of Estrogenic Toxicants 1995
- The Role of Medical Management in the Treatment of Endometriosis 1995
- Immunoresponsiveness in endometriosis: implications of estrogenic toxicants 1995
- Sonographic assessment of nongravid female macaques (Macaca mulatta and Macaca fascicularis) 1992
- Pathogenesis of endometriosis 1992
- Radiation-induced endometriosis in Macaca mulatta 1991
- The immune system in endometriosis 1991
- Immunologie Aspects of Endometriosis 1989
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