Chlorinated Hydrocarbons in Infertile Women

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This study investigated the presence and levels of chlorinated hydrocarbons in infertile women, reporting significant associations between specific compounds and reproductive health outcomes.

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Abstract

This study was conducted to investigate the hypothesis that chlorinated hydrocarbons (CHC) may affect fertility in women. In 489 infertile women, CHC levels were measured in whole blood. Different anamnestic and clinical parameters were obtained or investigated in order to detect possible associations to CHC concentrations. CHC levels were correlated to the women's age, body mass index, and nationality. Especially in women with uterine fibroids, endometriosis, miscarriages, persistent infertility, and hormonal disturbances, elevated concentrations of chlorinated hydrocarbons with long half-lives were observed. Chlorinated hydrocarbons may play a role in female infertility and may be an underlying factor in certain gynecological conditions.

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Condition tags

endometriosis

MeSH descriptors

Hydrocarbons, Chlorinated Infertility, Female Abortion, Spontaneous Abortion, Spontaneous Abortion, Spontaneous Adult Age Factors Body Mass Index Endocrine System Diseases Endocrine System Diseases Endometriosis Endometriosis Endometriosis Environmental Exposure Female Germany Half-Life Humans Hydrocarbons, Chlorinated Hydrocarbons, Chlorinated

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References (51)

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Source provenance

europepmc
last seen: 2026-09-21T06:08:07.822426+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:10:29.640636+00:00
License: CC0 · commercial use OK