Role of Environmental Pollutants in Endometriosis
This review highlights environmental pollutants like dioxins, pesticides, and bisphenols as potential contributors to endometriosis etiology and pathogenesis.
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This paper is a narrative review examining how environmental pollutants, especially endocrine-disrupting compounds such as dioxins, organochlorine pesticides, bisphenols, and phthalates, may influence the onset and progression of endometriosis in both human and animal contexts. It highlights mechanistic pathways centered on endocrine and reproductive disruption, including aryl hydrocarbon receptor signaling, and summarizes epidemiologic and experimental findings while noting that study results are contradictory. A key limitation explicitly emphasized is the inconsistency across reviewed studies, which complicates drawing definitive conclusions. This paper is centrally about endometriosis — it reviews evidence linking environmental toxicant exposure (e.g., dioxins and other endocrine disruptors) to endometriosis pathogenesis and etiology.
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References (58)
- Analysis of cytokines in the peritoneal fluid of endometriosis patients as a function of the menstrual cycle stage using the Bio-Plex® platform via openalex
- Aromatase: a key molecule in the pathophysiology of endometriosis and a therapeutic target via openalex
- Aromatase expression in endometriosis. via openalex
- Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis via openalex
- Dioxin and Endometrial Progesterone Resistance via openalex
- Effect of TCDD Exposure on CYP1A1 and CYP1B1 Expression in Explant Cultures of Human Endometrium via openalex
- Endometriosis and Organochlorinated Environmental Pollutants: A Case–Control Study on Italian Women of Reproductive Age via openalex
- Endometriosis in Rhesus Monkeys (Macaca mulatta) Following Chronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin via openalex
- Estrogen-independent actions of environmentally relevant AhR-agonists in human endometrial epithelial cells via openalex
- Estrogen Receptor-β, Estrogen Receptor-α, and Progesterone Resistance in Endometriosis via openalex
- Expression of Ah Receptor and Dioxin-Related Genes in Human Uterine Endometrium in Women with or without Endometriosis. via openalex
- GSTM1 null polymorphism and susceptibility to endometriosis and ovarian cancer via openalex
- Histomorphometric alteration and cell-type specific modulation of arylhydrocarbon receptor and estrogen receptor expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin and 17β-estradiol in mouse experimental model of endometriosis via openalex
- Identifying Subsets of Complex Mixtures Most Associated With Complex Diseases via openalex
- Immune interactions in endometriosis via openalex
- Induction of endometriosis in mice: A new model sensitive to estrogen via openalex
- Interaction between cytochrome P450 gene polymorphisms and serum organochlorine TEQ levels in the risk of endometriosis via openalex
- Linkage and association studies of the relationship between endometriosis and genes encoding the detoxification enzymes GSTM1, GSTT1 and CYP1A1 via openalex
- Possible aggravating impact of gene polymorphism in women with endometriosis. via openalex
- Possible involvement of arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1 genes in the development of endometriosis via openalex
- Proton irradiation and endometriosis. via openalex
- Role of Progesterone Antagonists and New Selective Progesterone Receptor Modulators in Reproductive Health via openalex
- Serum Levels of TCDD and Dioxin-like Chemicals in Rhesus Monkeys Chronically Exposed to Dioxin: Correlation of Increased Serum PCB Levels with Endometriosis via openalex
- Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice. via openalex
- The link between environmental toxicant exposure and endometriosis via openalex
- The Physiopathology of Endometriosis: Pollution and Dioxin via openalex
- The Potential Role of Environmental Toxins in the Pathophysiology of Endometriosis via openalex
- Treatment of Severe Postmenopausal Endometriosis With an Aromatase Inhibitor via openalex
- W2088590274 via openalex
- W1989540595 via openalex
- W2096666806 via openalex
- W2099726999 via openalex
- W2106212380 via openalex
- W2111476630 via openalex
- W1976846448 via openalex
- W1970094142 via openalex
- W1967868552 via openalex
- W2134753968 via openalex
- W1924541162 via openalex
- W2144786108 via openalex
- W2154746134 via openalex
- W1600605923 via openalex
- W2166088212 via openalex
- W2183313539 via openalex
- W2304131176 via openalex
- W4232798756 via openalex
- W4255645971 via openalex
- W4400948341 via openalex
- W6633862455 via openalex
- W2043964379 via openalex
- W6656356435 via openalex
- W2046746600 via openalex
- W2057133049 via openalex
- W2038052638 via openalex
- W2032519662 via openalex
- W2068684749 via openalex
- W2013857643 via openalex
- W2075734115 via openalex
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