External validation of the Endometriosis Fertility Index in a French population

Boujenah J, Jeremy Boujenah, J. Boujenah, Bonneau C, Claire Bonneau, Hugues JN, Jean-Noel Hugues, Jean‐Noël Hugues, Christophe Sifer, Sifer C, C. Sifer, Poncelet C, Christophe Poncelet, C. Poncelet
Fertility and sterility · 2015 · vol. 104(1) , pp. 119–123.e1 · doi:10.1016/j.fertnstert.2015.03.028 · PMID:25935492 · W1984469907
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This study externally validated the Endometriosis Fertility Index in a French population to assess its applicability to diverse patient groups.

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Abstract

OBJECTIVE: To show an external validation of the Endometriosis Fertility Index (EFI) and to observe cumulated pregnancy rates after infertility management combining surgery and assisted reproductive technologies (ART). DESIGN: Observational study from January 2004 to December 2012. SETTING: Tertiary-care university hospital and ART center. PATIENT(S): Four hundred twelve infertile and endometriotic patients after laparoscopic surgery. INTERVENTION(S): Surgical diagnosis and treatment followed by spontaneous fertility or ART management. MAIN OUTCOME MEASURE(S): Spontaneous pregnancy rates and cumulative (spontaneous and ART) pregnancy rates according to the EFI. RESULT(S): A significant relationship between EFI and spontaneous pregnancy rates was observed at 12 months (P=.001). The least function score and complete removal of endometriotic lesions and pelvic adhesions were significantly associated with spontaneous pregnancy (P=.006). Cumulative pregnancy rate at 18 months was 78.8%. ART benefits for pregnancy rates were higher for patients with poor EFI. CONCLUSION(S): External validation of the EFI in a French population was demonstrated. Combining surgery for endometriosis and ART led to a 78.8% pregnancy rate at 18 months after surgery.

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Condition tags

endometriosis

MeSH descriptors

Birth Rate Endometriosis Endometriosis Infertility, Female Infertility, Female Population Surveillance Population Surveillance Population Surveillance Adult Adult Birth Rate Birth Rate Double-Blind Method Double-Blind Method Endometriosis Endometriosis Endometriosis Female Female Follow-Up Studies

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References (36)

Cited by (47)

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