Modified endometriosis fertility index is more accurate to predict the non-ART pregnancy rate following surgery: a cohort of Chinese women

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AI-generated summary by claude@2026-06+body, 2026-06-09

A modified endometriosis fertility index demonstrated higher predictive accuracy for non-ART pregnancy rates post-surgery in infertile Chinese women compared to the original index.

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AI-generated deep summary by claude@2026-06, 2026-06-09

This retrospective cohort study evaluated whether a modified endometriosis fertility index (EFI), recalibrated using population-specific optimal cutoffs and weights, could better predict the non–assisted reproductive technology (non-ART) pregnancy rate after laparoscopic surgery in 564 infertile Chinese women with endometriosis. The authors used 472 patients to modify the EFI and then tested predictive accuracy in an independent set of 92 patients, using multivariable Cox regression and C-index comparisons, while also assessing specific predictor contributions (historical vs surgical factors) and the role of prior pregnancy. Across the modification cohort, historical factors contributed more than surgical factors to non-ART pregnancy prediction in both the modified EFI and the original EFI, and prior pregnancy was not significantly associated with post-operative non-ART pregnancy rates in either version. Predictive accuracy improved for the modified EFI compared with the original EFI in both internal evaluation and an external time-based population (2018), though the study’s retrospective design and split-sample calibration/validation approach are caveats. This paper is centrally about endometriosis — it modifies and validates the endometriosis fertility index to predict non-ART pregnancy after endometriosis surgery in Chinese women.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Fertility Pregnancy Rate Adult China Cohort Studies Endometriosis Female Fertility Humans Pregnancy Pregnancy Rate

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