Classification and Clinical Staging of Endometriosis
The #ENZIAN classification provides a comprehensive, reproducible system for describing peritoneal, ovarian, and deep infiltrating endometriosis and adhesions, improving surgical planning and disease assessment.
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This paper reviews how endometriosis classification systems have been developed and compares the rASRM, EFI, and ENZIAN approaches, including how they perform for clinical staging, non-invasive diagnostics, and characterization of lesion location and deep infiltrating disease. The authors report that rASRM does not correlate well with symptoms or other parameters and lacks non-invasive diagnostic utility, while EFI focuses on pregnancy probability without detailed lesion mapping; by contrast, ENZIAN can be applied with MRI/TVS to assess surgical difficulty and risk, and the updated #ENZIAN system adds more comprehensive, reproducible anatomic description of peritoneal and ovarian disease and deep endometriosis. A stated caveat is that each existing system has specific gaps in correlating with symptoms and in covering lesion distribution. This paper is centrally about endometriosis — it focuses specifically on the classification and clinical staging of endometriosis and how updated systems like #ENZIAN improve non-invasive and surgical description.
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