Assessing research gaps and unmet needs in endometriosis

Sawsan As-Sanie, Sawsan As‐Sanie, Black R, Rebecca Black, Linda C. Giudice, Giudice LC, Tanika Gray Valbrun, Gray Valbrun T, Jhumka Gupta, Gupta J, Brittany Jones, Jones B, Laufer MR, Marc R. Laufer, Alexandra Milspaw, Alexandra T Milspaw, Milspaw AT, Missmer SA, Stacey A. Missmer, Abby Norman, Norman A, Robert N. Taylor, Taylor RN, Kedra Wallace, Wallace K, Zev Williams, Paul J. Yong, Rebecca A. Nebel, Nebel RA
American journal of obstetrics and gynecology · 2019 · vol. 221(2) , pp. 86–94 · doi:10.1016/j.ajog.2019.02.033 · PMID:30790565 · W2916443849
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This paper identifies existing research gaps and unmet needs within the field of endometriosis to guide future study and clinical practice.

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Abstract

Endometriosis, a systemic disease that is often painful and chronic, affects ∼10% of reproductive-age women. The disease can have a negative impact on a patient's physical and emotional well-being, quality of life, and productivity. Endometriosis also places significant economic and social burden on patients, their families, and society as a whole. Despite its high prevalence and cost, endometriosis remains underfunded and underresearched, greatly limiting our understanding of the disease and slowing much-needed innovation in diagnostic and treatment options. Due in part to the societal normalization of women's pain and stigma around menstrual issues, there is also a lack of disease awareness among patients, health care providers, and the public. The Society for Women's Health Research convened an interdisciplinary group of expert researchers, clinicians, and patients for a roundtable meeting to review the current state of the science on endometriosis and identify areas of need to improve a woman's diagnosis, treatment, and access to quality care. Comprehensive and interdisciplinary approaches to disease management and increased education and disease awareness for patients, health care providers, and the public are needed to remove stigma, increase timely and accurate diagnosis and treatment, and allow for new advancements.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal Biomarkers Biomarkers Contraceptive Agents, Hormonal Contraceptive Agents, Hormonal Delayed Diagnosis Denervation Diagnostic Errors Endometriosis Endometriosis Estrogen Antagonists Estrogen Antagonists Female Humans Hysterectomy Laparoscopy Magnetic Resonance Imaging Pelvic Pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (50)

Source provenance

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License: CC0 · commercial use OK