Is there any correlation between stages of endometriosis and severity of chronic pelvic pain? Possibilities of treatment

Gyorgy Szendei, Szendei G, György Szendei, Z. Hernádi, Hernádi Z, Zsolt Hernádi, N. Dévényi, Dévényi N, Nóra Dévényi, Zsolt Csapó, Csapó Z
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2005 · vol. 21(2) , pp. 93–100 · doi:10.1080/09513590500107660 · PMID:16109595 · W2081676598
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This study found no correlation between endometriosis stage and chronic pelvic pain severity, but continuous oral contraceptive use significantly reduced pain and the need for hysterectomy.

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Abstract

We report herein findings on 181 patients, suffering from pelvic endometriosis confirmed by histology, whose main symptom was chronic pelvic pain (CPP). They attended the outpatient clinic at the 1st Department of Obstetrics and Gynaecology, Semmelweis University in Budapest, between 1 January 1995 and 1 January 2000. The extent of pelvic endometriosis was determined on the basis of the 1985 revised scoring system of the American Fertility Society (R-AFS). The short form of the McGill pain questionnaire was used for the evaluation of CPP. After the first operative intervention, therapy with a gonadotropin-releasing hormone (GnRH) analog was given for 6 months. Second-look laparoscopy was performed 8-10 weeks after the end of GnRH-analog treatment, which was followed by a non-conventionally administered, monophasic oral contraceptive (OC) treatment. In the long term, 118 patients received the non-conventionally administered, monophasic OC treatment, which contained a third-generation progestogen, to be taken continuously for at least 6 months. The other 63 patients who did not receive OC treatment for one reason or another were evaluated as a control group. We analyzed data on CPP before the first surgical intervention, then following therapy with the GnRH analog at the second-look operation, and then after 6, 12, 18 and 24 months. We also reviewed potential causes of CPP, especially focused on endometriosis. No correlation was found between the stage of endometriosis according to R-AFS score and the severity of CPP. At the 24-month follow-up after second-look laparoscopy, the non-conventionally administered monophasic OC treatment was found not only to significantly reduce pain scores, but also the required radical operative solution (hysterectomy plus bilateral adnexectomy) for CPP by OC users.

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Condition tags

dysmenorrheadyspareuniaendometriosischronic_pelvic_pain

MeSH descriptors

Contraceptives, Oral, Combined Endometriosis Gonadotropin-Releasing Hormone Pelvic Pain Combined Modality Therapy Contraceptives, Oral, Combined Contraceptives, Oral, Combined Drug Administration Schedule Dysmenorrhea Dysmenorrhea Dyspareunia Dyspareunia Endometriosis Endometriosis Endometriosis Female Gonadotropin-Releasing Hormone Humans Laparoscopy Pain Measurement

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (41)

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