Impact of endometriosis on quality of life, anxiety, and depression: an Austrian perspective

F Friedl, David Riedl, D Riedl, S Fessler, L Wildt, Maria Hildegard Walter, M Walter, Rolf Richter, R Richter, G Schüßler, Gerhard Schüßler, B Böttcher, Bettina Böttcher
Archives of gynecology and obstetrics · 2015 · vol. 292(6) , pp. 1393–1399 · doi:10.1007/s00404-015-3789-8 · PMID:26112356 · W818630697
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-12 ⓘ

This Austrian survey of 62 endometriosis patients found moderate to severe anxiety in 29% and depressive symptoms in 14.5%, with significantly better quality of life scores compared to other international samples.

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This cross-sectional Austrian survey studied 62 patients with diagnosed endometriosis recruited from a tertiary care center, using standardized questionnaires: SF-36 for quality of life, HADS-D for anxiety and depression symptoms, and EHP-30 for endometriosis-specific health status. The study found that 29% had moderate-to-severe anxiety symptoms, 14.5% had depressive symptoms, and both occurred in 12.9%, while anxiety/depression and quality-of-life scores were also compared with 61 healthy controls using t-tests/ANCOVA and with published endometriosis samples from Oxford and Berlin using EHP-30 subscale comparisons. The authors report that quality-of-life impact in their cohort was considerably less than in other studies but similar to other chronic medical conditions, and that age significantly influenced mental health and emotional role functioning. A key limitation is the cross-sectional design and reliance on questionnaire-based symptom measures without a stated control for causal factors. This paper is centrally about endometriosis — assessing its impact on quality of life, anxiety, and depression in an Austrian patient sample.

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Abstract

Purpose Several studies on the quality of life in patients with endometriosis have been performed with conflicting results. This cross-section survey examines the influence of endometriosis on the psychological well-being and the quality of life and the incidence of anxiety and depression among these patients, recruited from a tertiary care center in Austria.

Methods

Three standardized questionnaires of 62 patients with endometriosis were evaluated: status of health questionnaire (SF-36), hospital anxiety and depression scale (HADS-D), and endometriosis health profile (EHP-30). Quality of life status (EHP-30) was compared with published samples of the Oxford hospital and the Charite Berlin. Chi-square tests, independent sample t-tests, and one-way independent ANCOVA’s were used to compare SF- 36 and HADS- D scores to 61 healthy controls. Pearson product-moment-correlation coefficients were used to investigate correlations between symptoms of depression and anxiety in the patient sample.

Results

Moderate to severe anxiety symptoms were found in 29 %; depressive symptoms were present in 14.5 % of the patients. Both symptoms occurred in 12.9 %. We found significant better values in all subscales of the EHP compared to the Oxford and Berlin samples. The control sample showed significant better subjective general health (p < 0.001), vitality (p < 0.001), mental health (p < 0.001), and better emotional role functioning (p < 0.001). Participants age significantly influenced mental health and emotional role functioning.

Conclusions

The impact of endometriosis on life quality in our study was considerably less than in other studies but equivalent to other chronic medical conditions. It could be shown that endometriosis is influenced by biopsychosocial variables. However, the elevated presence of anxiety and depressive symptoms indicates the need of psychosomatic treatment of affective disorders to prevent manifestation. Similar content being viewed by others

References

Brandes I (2007) Lebensqualität von Endometriose-Patientinnen. Geburtshilfe und Frauenheilkunde 67(11):1227–1231 Hudelist G, Fritzer N, Thomas A, Niehues C, Oppelt P, Haas D, Tammaa A, Salzer H (2012) Diagnostic delay for endometriosis in Austria and Germany: causes and possible consequences. Hum Reprod 27:3412–3416 Leyendecker G, Bilgicyildirim A, Inacker M, Stalf T, Huppert P, Mall G, Böttcher B, Wildt L (2014) The pathophysiology of adenomyosis and endometriosis Further insights into the mechanisms of uterine auto-traumatisation An MRI study. Arch Gynecol Obstet. doi:10.1007/s00404-014-3437-8 Leyendecker G, Wildt L, Mall G (2009) The pathophysiology of endometriosis and adenomyosis: tissue injury and repair. Arch Gynecol Obstet 280(4):529–538 WHO (1997). Programme on mental health: WHOQOL, measuring quality of life, WHO/MSA/MNH/PSF/97.4, http://www.who.int/mental_health/media/68.pdf (15.02.2014) Siedentopf F, Tariverdian N, Rucke M, Kentenich H, Arck PC (2008) Immune status, psychosocial distress and reduced quality of life in infertile patients with endometriosis. Am J Reprod Immunol 60(5):449–461 Nnoaham KE, Hummelshoj L, Webster P, D’Hooghe T, de Cicco NF, de Cicco NC, Jenkinson C, Kennedy SH, Zondervan KT (2011) Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries. Fertil Steril 96(2):366–373 De Graaff AA, Hooghe TMD, Dunselman GAJ, Dirksen CD, Hum-meldshoj L, WERF EndoeCost Consortium and Simoens S (2013) The significant effect of endometriosis on physical, mental and social wellbeing: results from an international cross-sectional survey. Hum Reprod 38(10):2677–2685 Sepulcri RDP, Amaral VFD (2009) Depressive symptoms, anxiety, and qual- ity of life in women with pelvic endometriosis. Eur J Obstet Gynecol Reprod Biol 142(1):53–56 Eriksen HLF, Gunnersen KF, Sørensen JA, Munk T, Nielsen T, Knudsen UB (2008) Psychological aspects of endometriosis: differences between patients with or without pain on four psychological variables. Eur J Obstet Gynecol Reprod Biol 139(1):100–105 Schute LK (2011) Prävalenz von Depressionen und Angststörungen und ihre Einflussfaktoren bei Frauen mit Endometriose. Unveröff. Diss., Medizinische Fakultät Charité-Universitätsmedizin, Berlin Bullinger M (2000) Erfassung der gesundheitsbezogenen Lebensqualität mit dem SF36-Health Survey. Bundesgesundheitsblatt-Gesundheitsforschung Gesundheitsschutz 43(3):190-197 Herrmann-Lingen C, Buss U, Snaith P (2005) HADS-D Hospital Anxiety and depression scale deutsche version: manual. Bern Hans Huber Jones G, Jenkinson C, Kennedy S (2001) The endometriosis health profile user manual. Nuffield department of obstetrics and gynaecology and Health Services Research Unit University of Oxford Schüßler G, Heuft G (2008) Anxiety and depresssion in patients with medical diseases. Zeitschrift für Psychosomatische Medizin und Psychotherapie 54(4):354–367 Deutskens E, de Ruyter K, Wetzels M, Oosterveld P (2004) Response rate and response quality of internet-based-surveys an experimental study. Mark Lett 15(1):21–36 Asch DA, Jedrziewski MK, Christakis NA (1997) Response rates to mail surveys published in medical journals. J Clin Epidemiol 50(10):1129–1136 Conflict of interest The authors report no conflict of interest. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Friedl, F., Riedl, D., Fessler, S. et al. Impact of endometriosis on quality of life, anxiety, and depression: an Austrian perspective. Arch Gynecol Obstet 292, 1393–1399 (2015). https://doi.org/10.1007/s00404-015-3789-8 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-015-3789-8

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Condition tags

endometriosis

MeSH descriptors

Anxiety Depression Endometriosis Quality of Life Adolescent Adult Anxiety Anxiety Austria Austria Berlin Berlin Case-Control Studies Cross-Sectional Studies Depression Depression Endometriosis Female Humans Male

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