Evaluation of Quality Of Life in Endometriosis Patients Before and After Surgical Treatment Using the EHP30 Questionnaire

Denise Tiringer, Alexandra Pedrini, Manuela Gstöttner, H Husslein, L Küssel, Alexandra Perricos, René Wenzl
In: Research Square · 2022 · doi:10.21203/rs.3.rs-1621018/v2 · W4281391655
preprint OA: green CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study found that surgical treatment significantly improved quality of life in endometriosis patients across pain, self-determination, emotional health, social environment, and self-image categories, with greater benefits for those with deep infiltrating endometriosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This paper evaluated health-related quality of life in 115 surgically confirmed endometriosis patients at the Medical University of Vienna by having participants complete the Endometriosis Health Profile-30 (EHP-30) one day after surgery (questions referencing the prior 4 weeks) and again 6–10 weeks postoperatively, then comparing changes across endometriosis subtypes. Postoperatively, scores improved significantly in all five EHP-30 categories (pain, self-determination, emotional health, social environment, and self-image), but patients with only peritoneal endometriosis showed no significant changes. When stratified by disease form, deep infiltrating endometriosis (DIE) and DIE plus ovarian endometrioma had greater improvements than ovarian endometrioma without DIE, and the authors’ analysis is limited by missing postoperative data that excluded many screened patients. This paper is centrally about endometriosis — it quantifies EHP-30 quality-of-life changes after surgical treatment across endometriosis subtypes.

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Abstract

Abstract Backround: Endometriosis is one of the most common gynaecological illnesses causing extensive psychological, physical and social impact on patient´s life and exerts negative effects on health-related quality of Life (HRQoL). However, the effects of surgery on the postoperative HRQoL in the different endometriosis subgroups have not been fully evaluated. Methods: We performed a comparative retrospective study between 2014 and 2018 at the Medical University of Vienna, including all patients with surgically confirmed endometriosis who had completed the standardized Endometriosis Health Profile - 30 (EHP-30) questionnaire one day after surgery (the questions refer to the four weeks preoperatively) and six to ten weeks postoperatively. Results: Compared to preoperative values, we found significant benefits, regarding postoperative conditions, in our study group (n=115) in all five categories, “pain” (HR 0.78, p<0.001); “self-determination” (HR 0,92, p<0.001); “emotional health” (HR 0,83, p<0.001);” social environment” (HR 0,67, p<0.001); and “self-image” (HR 0,47, p<0,001). Patients with only peritoneal endometriosis had the lowest preoperative clinical symptoms and there were no significant changes in any of the categories. In the subgroups deep infiltrating endometriosis (DIE) and DIE + ovarian endometrioma, surgical intervention results in a significantly greater improvement in all categories of EHP 30 compared to ovarian endometrioma without DIE or peritoneal endometriosis. Conclusion: Our study shows, that especially women with DIE - with or without ovarian endometrioma - demonstrate a more pronounced benefit from surgical therapy compared to patients with peritoneal endometriosis or endometrioma without DIE.

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Outcome instruments

EHP-30

Condition tags

endometriosisdie_deep_infiltratingendometrioma

Citation neighborhood

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References (13)

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