Peritoneal fluid interleukin-6 in women with chronic pelvic pain

Andrea J. Rapkin, A Rapkin, Rapkin A, Melinda Morgan, M Morgan, Morgan M, Bonpane C, Colleen M. Bonpane, C Bonpane, O Martinez-Maza, Otoniel Martı́nez-Maza, Martinez-Maza O
Fertility and sterility · 2000 · vol. 74(2) , pp. 325–328 · doi:10.1016/s0015-0282(00)00653-1 · PMID:10927052 · W2077868127
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This study investigated peritoneal fluid interleukin-6 levels in women diagnosed with chronic pelvic pain.

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Abstract

OBJECTIVE: To determine the relationship between peritoneal fluid concentrations of interleukin-6 (IL-6) and chronic pelvic pain symptomatology in women with adhesions, endometriosis, or no obvious intraperitoneal pathology. DESIGN: Clinical research study. SETTING: Healthy volunteers in an academic research environment. PATIENT(S): Reproductive-aged women undergoing laparoscopy for the diagnosis of pelvic pain, infertility, or sterilization were selected. INTERVENTION(S): Peritoneal fluid was collected at the time of the laparoscopy and later assayed for IL-6. Subjects completed a pelvic pain questionnaire, and operative reports were used to obtain the underlying diagnosis. MAIN OUTCOME MEASURE(S): Interleukin-6 concentrations. RESULT(S): No correlation between the presence or absence of pelvic pain, findings of adhesions or endometriosis, and the concentration of peritoneal fluid IL-6 was observed. CONCLUSION(S): The cytokine IL-6 does not seem to play a role in the genesis of chronic pelvic pain in women with adhesions or endometriosis.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Ascitic Fluid Interleukin-6 Pelvic Pain Ascitic Fluid Ascitic Fluid Endometriosis Endometriosis Endometriosis Endometriosis Female Female Humans Humans Interleukin-6 Interleukin-6 Interleukin-6 Laparoscopy Laparoscopy Ovarian Diseases Ovarian Diseases

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Cited by (27)

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